PMID: 7542688Aug 1, 1995Paper

Genetic variation among Pneumocystis carinii hominis isolates in recurrent pneumocystosis

The Journal of Infectious Diseases
S P KeelyA G Smulian

Abstract

Pneumocystis carinii hominis is a ubiquitous organism that causes pneumonia in immunocompromised persons. Paired P. carinii hominis isolates from human immunodeficiency virus-infected persons who had two episodes of pneumocystosis were examined for genetic heterogeneity. Genetic variation was detected by sequence comparison of a portion of the mitochondrial ribosomal RNA gene. In 5 of 10 patients experiencing two episodes of pneumocystosis, genetically distinct isolates were associated with each episode. These included 4 of 6 patients whose second episode of pneumocytosis occurred > 6 months after their initial bout. The genetic data support the hypothesis that some recurrent episodes of P. carinii hominis pneumonia are caused by reinfection rather than by reactivation of latent infection.

Citations

Mar 21, 1998·International Journal for Parasitology·E S Kaneshiro
Feb 5, 2002·Microbes and Infection·Alison MorrisLaurence Huang
Nov 26, 2003·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Olga MatosFrancisco Antunes
Feb 21, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Cristina MussiniUNKNOWN Changes in Opportunistic Prophylaxis (CIOP) Study Group
Apr 21, 2005·MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports·Constance A BensonUNKNOWN Infectious Diseases Society of America
Jun 1, 1997·AIDS Patient Care and STDs·R P BaughmanJ R Stringer
Jun 5, 1998·The Pediatric Infectious Disease Journal·F P PolackR E Willoughby
Jan 1, 1997·APMIS. Supplementum·P M HauserP Francioli
Nov 26, 2003·Antimicrobial Agents and Chemotherapy·Robert F MillerAnn E Wakefield
Oct 31, 2000·Applied and Environmental Microbiology·R J PalmerA E Wakefield
Nov 5, 1999·Clinical and Diagnostic Laboratory Immunology·E S KaneshiroB Lundgren
Apr 12, 2012·Clinical Microbiology Reviews·Alison Morris, Karen A Norris
Feb 13, 2001·Infection and Immunity·J R Stringer, S P Keely
Apr 17, 2009·Journal of Clinical Microbiology·Sebastiaan J van HalJock Harkness
Sep 28, 2001·Journal of Clinical Microbiology·J Helweg-LarsenJ D Lundgren
Mar 30, 2002·Journal of Clinical Microbiology·Robert F MillerAnn E Wakefield
Aug 3, 2005·Thorax·R F MillerA E Wakefield
Nov 9, 2000·American Journal of Respiratory and Critical Care Medicine·J M Beck
Dec 5, 2012·PLoS Pathogens·Francis Gigliotti, Terry W Wright
Dec 22, 2009·Future Microbiology·Michelle N Kelly, Judd E Shellito
Aug 21, 2010·Future Microbiology·Olga Matos, Francisco Esteves
Apr 1, 1996·Emerging Infectious Diseases·C B Beard, T R Navin
Aug 27, 2002·Emerging Infectious Diseases·James R StringerAnn E Wakefield
Jan 21, 2003·Emerging Infectious Diseases·Elodie Senggen ManoloffPhilippe M Hauser
Oct 27, 2004·Emerging Infectious Diseases·Charles Ben BeardBettina Lundgren
Mar 9, 2005·Emerging Infectious Diseases·Francisco J MedranoEnrique J Calderon
Sep 21, 2013·Emerging Infectious Diseases·Serena FongLaurence Huang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.