Genetics and Evolution of Mammalian Coat Pigmentation.

Annual Review of Animal Biosciences
Eduardo Eizirik, Fernanda J Trindade

Abstract

The diversity of mammalian coat colors, and their potential adaptive significance, have long fascinated scientists as well as the general public. The recent decades have seen substantial improvement in our understanding of their genetic bases and evolutionary relevance, revealing novel insights into the complex interplay of forces that influence these phenotypes. At the same time, many aspects remain poorly known, hampering a comprehensive understanding of these phenomena. Here we review the current state of this field and indicate topics that should be the focus of additional research. We devote particular attention to two aspects of mammalian pigmentation, melanism and pattern formation, highlighting recent advances and outstanding challenges, and proposing novel syntheses of available information. For both specific areas, and for pigmentation in general, we attempt to lay out recommendations for establishing novel model systems and integrated research programs that target the genetics and evolution of these phenotypes throughout the Mammalia.

References

Jan 1, 1994·Annual Review of Genetics·I J Jackson
Sep 1, 1995·Mammalian Genome : Official Journal of the International Mammalian Genome Society·H KlunglandS Lien
Apr 1, 1996·Mammalian Genome : Official Journal of the International Mammalian Genome Society·H JoergG F Stranzinger
Aug 1, 1996·Trends in Genetics : TIG·G S Barsh
Mar 2, 1999·Mammalian Genome : Official Journal of the International Mammalian Genome Society·S MarklundL Andersson
Mar 25, 2000·American Journal of Human Genetics·R M HardingJ L Rees
Sep 22, 2001·Current Biology : CB·K RitlandH D Marshall
Apr 1, 1973·Journal of the History of Biology·E Mayr
Mar 7, 2003·Current Biology : CB·Eduardo EizirikStephen J O'Brien
Apr 16, 2003·Molecular Ecology·H E Hoekstra, M W Nachman
Apr 22, 2003·Proceedings of the National Academy of Sciences of the United States of America·Michael W NachmanSusan L D'Agostino
Oct 31, 2003·Trends in Genetics : TIG·Michael E N Majerus, Nicholas I Mundy
Jul 11, 2006·Science·Hopi E HoekstraJanet P Crossland
Jul 6, 2007·The Journal of Investigative Dermatology·Roman J GarciaLidia Kos
Oct 20, 2007·Science·Sophie I CandilleGregory S Barsh
Nov 19, 2008·Nature Reviews. Genetics·Zhong WangMichael Snyder
Feb 7, 2009·Science·Tovi M AndersonGregory S Barsh
Jul 25, 2009·Pigment Cell & Melanoma Research·Catherine D Van RaamsdonkShosuke Ito
Aug 1, 2009·The Journal of Heredity·Helen McRobieJo Kelly
Aug 4, 2009·PloS One·Evan P KingsleyHopi E Hoekstra
Apr 13, 2010·Trends in Genetics : TIG·Joanna K HubbardRebecca J Safran
May 7, 2010·Proceedings of the National Academy of Sciences of the United States of America·Nina G Jablonski, George Chaplin
Jun 4, 2010·Pigment Cell & Melanoma Research·Chris Kaelin, Greg Barsh
Oct 22, 2010·Proceedings. Biological Sciences·William L AllenRoland Baddeley
Jan 1, 1988·Trends in Ecology & Evolution·R A Kiltie
Feb 26, 2011·Science·Marie ManceauHopi E Hoekstra
Aug 17, 2011·Genome Research·Lewis Z HongGregory S Barsh
Oct 19, 2011·Nature Reviews. Genetics·Rowan D H Barrett, Hopi E Hoekstra
Sep 22, 2012·Science·Christopher B KaelinMarilyn Menotti-Raymond
Dec 20, 2012·PloS One·Alexsandra SchneiderEduardo Eizirik
Apr 10, 2013·Seminars in Cell & Developmental Biology·Tim Caro
May 28, 2013·Current Biology : CB·Xiao XuShu-Jin Luo
Jun 14, 2013·BMC Genomics·Ruiwen FanChangsheng Dong
Dec 3, 2013·Current Biology : CB·Tatiane C TrigoEduardo Eizirik
Apr 3, 2014·Nature Communications·Tim CaroTheodore Stankowich
May 6, 2014·The Journal of Heredity·Philip W HedrickDick Dekker
May 27, 2014·Biology Open·Jana KraussChristiane Nüsslein-Volhard

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Citations

Sep 15, 2021·Proceedings of the National Academy of Sciences of the United States of America·Vinay SagarUma Ramakrishnan
Oct 9, 2021·Proceedings of the National Academy of Sciences of the United States of America·Eduardo Eizirik

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