Genetics of birdshot chorioretinopathy

Seminars in Ophthalmology
Raymond Wee, George Papaliodis

Abstract

Birdshot chorioretinopathy is a bilateral, posterior uveitis that affects primarily Caucasians. Although the genetic basis of disease is not completely understood, certain factors are known, such as the strong association with human leukocyte antigen (HLA)-A29. However, given the prevalence of the HLA-A29 allele in the general population, if it were the only factor required for disease, many more people would have birdshot chorioretinopathy. It has been suggested that some environmental factor may trigger this disease entity in those who are genetically predisposed based on inheritance of the HLA-A29 allele.

References

Oct 1, 1992·Acta Ophthalmologica·M Fich, T Rosenberg
Jan 15, 1992·American Journal of Ophthalmology·P LeHoangJ H Cohen
Jan 1, 1992·Immunogenetics·L P de WaalH A Priem
Aug 15, 1990·American Journal of Ophthalmology·M D de SmetR B Nussenblatt
Jan 1, 1990·Current Eye Research·G S BaarsmaA Kijlstra
Feb 15, 1988·American Journal of Ophthalmology·H A PriemJ A Oosterhuis
Jan 15, 1986·Documenta Ophthalmologica. Advances in Ophthalmology·G S BaarsmaA Rothova
Aug 1, 1982·American Journal of Ophthalmology·R B NussenblattA E Maumenee
Jan 1, 1980·American Journal of Ophthalmology·S J Ryan, A E Maumenee
Feb 15, 1993·American Journal of Ophthalmology·M S Suttorp-SchultenA Rothova
Jul 9, 1999·The British Journal of Ophthalmology·A T GaschS M Whitcup
Feb 28, 2001·Proceedings of the National Academy of Sciences of the United States of America·Y SzpakM Pla
Oct 19, 2004·American Journal of Ophthalmology·Ralph D LevinsonGary N Holland
Oct 30, 2004·Current Opinion in Immunology·Urs Christen, Matthias G von Herrath
Nov 3, 2005·Survey of Ophthalmology·Kayur H ShahGary N Holland
Jan 3, 2006·American Journal of Ophthalmology·Ralph D LevinsonGary N Holland
Jul 5, 2006·Survey of Ophthalmology·Heinrich M HolakSophie A Holak
Oct 27, 2006·Current Opinion in Ophthalmology·Dominique Monnet, Antoine P Brézin

❮ Previous
Next ❯

Citations

Nov 24, 2011·Ocular Immunology and Inflammation·Antoine P BrézinRalph D Levinson
Dec 10, 2015·Ocular Immunology and Inflammation·Blanca MolinsAlfredo Adán
May 17, 2011·American Journal of Ophthalmology·Jonas J W KuiperAniki Rothova
Aug 3, 2011·Progress in Retinal and Eye Research·Marc D de SmetSue Lightman
Mar 21, 2017·The British Journal of Ophthalmology·Carl P HerbortMarina Papadia
Nov 14, 2019·Ocular Immunology and Inflammation·Edmund TsuiJohn A Gonzales

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Related Papers

Ocular Immunology and Inflammation
Antoine P BrézinRalph D Levinson
Bulletin de la Société belge d'ophtalmologie
H A Priem
American Journal of Ophthalmology
Jennifer E ThorneJames P Dunn
© 2021 Meta ULC. All rights reserved