Genetics of epilepsy

Handbook of Clinical Neurology
Danielle Nolan, John Fink

Abstract

Discovery of nearly 200 genes implicated in epilepsy and insights into the molecular and cellular pathways involved are transforming our knowledge of the causes, classifications, diagnosis, and in some cases, treatments for individuals with chronic seizure disorders. Numerous disorders once considered "idiopathic" are now recognized as genetic conditions. Despite these remarkable advances, the cause of epilepsy for most individuals is unknown. We present a clinical approach to patients with epilepsy, presenting an algorithm for clinical and genetic testing, and review genes implicated in epilepsy and their associated syndromes.

Citations

Oct 31, 2018·Journal of Cardiovascular Electrophysiology·Marek MalikUNKNOWN e-Rhythm Study Group of EHRA
Feb 15, 2019·Current Opinion in Neurology·Philip H Iffland, Peter B Crino
Aug 6, 2019·JAMA Neurology·Hugh KearneyNorman Delanty
Jan 23, 2020·Epilepsy Currents·Bernard S ChangUNKNOWN NINDS/AES Epilepsy Research Benchmark Stewards Committee
Jul 30, 2020·Cellular and Molecular Neurobiology·Diego A Forero
May 20, 2020·Pflügers Archiv : European journal of physiology·Ilaria RivoltaJacopo C DiFrancesco
Jan 17, 2020·International Journal of Molecular Sciences·Bruno SterliniAnna Corradi
Aug 30, 2019·American Journal of Medical Genetics. Part a·Natasha DarrasMaria R Cilio

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