PMID: 18412098DOI: 10.1002/ajmg.c.30169Apr 17, 2008Paper
Genetics of post-traumatic stress disorder: informing clinical conceptualizations and promoting future research.
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics
Nicole R NugentKarestan C Koenen
Abstract
The purpose of this article is to provide an overview of genetic research involving post-traumatic stress disorder (PTSD). First, we summarize evidence for genetic influences on PTSD from family investigations. Second, we discuss the distinct contributions to our understanding of the genetics of PTSD permitted by twin studies. Finally, we summarize findings from molecular genetic studies, which have the potential to inform our understanding of underlying biological mechanisms for the development of PTSD.
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