PMID: 2492220Jan 1, 1989Paper

Genetics of the partial epilepsies: a review

Epilepsia
R Ottman

Abstract

The research literature is consistent in reporting somewhat less familial aggregation in partial than in generalized epilepsy. However, relatives of patients with partial seizures do appear to have higher seizure risks than relatives of controls, suggesting that genetic factors are important in at least some partial epilepsies. Complex partial epilepsy appears to be only slightly less familial than other types of epilepsy. Relatives of patients with focal EEG abnormalities generally have been found to have lower risk of both EEG abnormalities and epilepsy than relatives of patients with generalized abnormalities. For focal temporocentral abnormalities, however, there is evidence of an important influence of genetic factors.

References

Sep 1, 1988·American Journal of Medical Genetics·D A GreenbergP I Terasaki
Oct 1, 1966·Electroencephalography and Clinical Neurophysiology·C OunstedS J Hutt
Jan 1, 1972·Epilepsia·E A Rodin
Mar 1, 1969·Epilepsia·M Beaussart, P Loiseau
Jan 1, 1971·Brain : a Journal of Neurology·S CurrieD F Scott
Sep 1, 1965·Archives of Neurology·P F Bray, W C Wiser
Jan 1, 1966·Southern Medical Journal·W P Wilson, B S Harris
Oct 17, 1966·JAMA : the Journal of the American Medical Association·E Rodin, S Gonzalez
Oct 29, 1964·The New England Journal of Medicine·P F BRAY, W C WISER
Oct 1, 1948·Archives of Neurology and Psychiatry·E L GIBBSB FUSTER

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Citations

Mar 31, 1998·Archives of Neurology·R OttmanN Risch
Aug 1, 1996·Annals of Neurology·S F BerkovicJ L Hopper
Apr 18, 1998·Annals of Neurology·S F BerkovicJ L Hopper
Oct 1, 1990·Journal of Neurology·N Senanayake
Mar 1, 1992·Epilepsy Research·N A JanjuaO Hatase
Apr 5, 1997·Lancet·S J Wallace
May 24, 2003·Seizure : the Journal of the British Epilepsy Association·A BianchiUNKNOWN LICE Episcreen Group
Mar 1, 1993·Seizure : the Journal of the British Epilepsy Association·N Buchanan, G Scambler
May 1, 1995·Nature Genetics·R OttmanM L Scheuer
Oct 30, 2012·The Journal of Biological Chemistry·Matthew R SapioLloyd D Fricker
Jun 14, 2003·The Neurologist·Melodie R Winawer
Apr 1, 1996·Epilepsia·R OttmanM Susser
Aug 29, 2000·Epilepsia·B A Neubauer
Jun 11, 2005·Epilepsia·Annick SalzmannAlain Malafosse
May 30, 2009·Epilepsia·Antonio GambardellaUmberto Aguglia
Jan 10, 2012·Epilepsia·Danya F VearsIngrid E Scheffer
Sep 8, 2012·Epilepsy Research and Treatment·Annick Salzmann, Alain Malafosse
Jun 23, 2011·PloS One·Kellen D WindenJerome Engel
Apr 30, 2013·PloS One·Saud AlhusainiGianpiero L Cavalleri
Sep 17, 2013·PloS One·Dennis LalBernd A Neubauer
Sep 1, 2012·Epilepsy Research and Treatment·Garima Shukla, Asuri N Prasad
Apr 6, 2012·Epilepsy Research·Sylwia Misiewicz, Melodie R Winawer
Nov 23, 2011·Brain & Development·Su-Kyeong Hwang, Shinichi Hirose
Jun 6, 2007·Neuroscience Letters·Ida MannaAldo Quattrone
Jul 6, 2004·Annals of Neurology·Lata VadlamudiSamuel F Berkovic
Jan 9, 2013·Epilepsia·Meng-Han TsaiIngrid E Scheffer
Feb 25, 2006·Epilepsy & Behavior : E&B·Melodie R Winawer
Jun 15, 2011·Epilepsy Research·Rui-Juan LvHui Liu
Apr 12, 2002·Seizure : the Journal of the British Epilepsy Association·Giovanni Regesta, Paolo Tanganelli
Oct 1, 1994·Journal of Child Neurology·J R Buchhalter
Feb 1, 1997·The Journal of Laryngology and Otology·R SabithaA Ramesh
Jun 1, 2010·The Laryngoscope·Isabelle Schrauwen, Guy Van Camp
Oct 6, 2000·Arquivos de neuro-psiquiatria·E KobayashiI Lopes-Cendes
Sep 1, 1995·Developmental Medicine and Child Neurology·P CuratoloE Medda
Dec 29, 2020·Neuropsychiatric Disease and Treatment·Langzi TanLili Long

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