Genital HPV in Children and Adolescents: Does Sexual Activity Make a Difference?

Journal of Pediatric and Adolescent Gynecology
Flora BacopoulouAthanasios Michos

Abstract

To compare the prevalence of human papillomavirus (HPV) genital infection among prepubertal children, sexually active and not sexually active adolescents, and assess potential risk factors for transmission. Prospective study. Outpatient adolescent health clinic. Ninety-five girls aged 2-21 years; 38 sexually active adolescents (group A), 28 not sexually active adolescents (group B), and 29 prepubertal children (group C). Participants' vaginal or cervical specimens were tested for HPV with the CLART HPV 2 assay (Clinical Array Technology, Genomica, Madrid, Spain) and for cytological abnormalities with liquid-based cytology. Differences in prevalence of low- and high-risk HPV infections among the 3 groups. Genital HPV was detected in 37.9% (36/95) of all participants; 47.4% (18/38) of group A, 28.6% (8/28) of group B, and 34.5% (10/29)of group C (P = .27). Multiple HPV infection was detected in 26.3% (10/38), 10.7% (3/28), and 13.8% (4/29) of groups A, B, and C, respectively (P = .21). High-risk genotypes were detected in 47.4% (18/38), 28.6% (8/28), and 24.1% (7/29) of groups A, B, and C, respectively (P = .10). Main high-risk genotypes were HPV 16 (27%, 10/37), HPV 31 (21.6%, 8/37 ), HPV 35 (13.5%, 5/37), HPV 53 (13.5%, 5/37), ...Continue Reading

References

Jan 1, 1992·American Journal of Obstetrics and Gynecology·C J TsengC C Pao
Aug 1, 1990·The Australian & New Zealand Journal of Obstetrics & Gynaecology·S K TayS K Lim-Tan
Jun 1, 1994·British Journal of Obstetrics and Gynaecology·F PakarianJ M Best
Feb 16, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Stuart CollinsCiaran B J Woodman
Apr 23, 2003·Cancer Letters·Antonio FregaAldo Vecchione
Jun 6, 2003·Pediatric Dermatology·Jennifer PowellFenella Wojnarowska
Jun 30, 2004·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Gail Hornor
Dec 21, 2004·The Journal of Infectious Diseases·Darron R BrownJ Dennis Fortenberry
Feb 3, 2005·The Journal of Infectious Diseases·Rachel L WinerLaura A Koutsky
Mar 9, 2005·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·John Cason, Christine A Mant
Oct 8, 2005·Seminars in Pediatric Infectious Diseases·Sara H Sinal, Charles R Woods
Nov 17, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Marjut A M RintalaStina M Syrjänen
Sep 11, 2007·Lancet·Mark SchiffmanSholom Wacholder
Dec 4, 2008·European Journal of Pediatrics·Ioannis N MammasDemetrios A Spandidos
Mar 10, 2009·American Journal of Obstetrics and Gynecology·Daniela DoerflerElmar A Joura
Aug 18, 2009·Public Health Genomics·Helen Trottier, Ann N Burchell
Apr 20, 2011·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Bree WeaverDarron Brown
May 21, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S TsiodrasP Karakitsos
May 9, 2012·Gynecologic Oncology·Lina MichalaEfstathia Panotopoulou
Aug 8, 2012·Archives of Pediatrics & Adolescent Medicine·Lea E WiddiceJessica A Kahn
Dec 5, 2012·Vaccine·John T SchillerSuzanne M Garland
Nov 29, 2013·Pediatric Dermatology·Maria GiannakiGeorge Chrousos
Jul 12, 2014·Oncology Letters·Ioannis N MammasDemetrios A Spandidos

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Citations

Aug 31, 2019·Epidemiology and Infection·Reyna Lizette Pacheco-DomínguezMalaquías López-Cervantes
Sep 19, 2020·International Journal of Impotence Research·Manuela Hiess
May 10, 2021·Transplantation and Cellular Therapy·Mark PartaDennis D Hickstein
Jan 3, 2018·Journal of Pediatric and Adolescent Gynecology·Joyce A AdamsNancy D Kellogg

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