Genitourinary small cell carcinoma: a retrospective review of treatment and survival patterns at The Ottawa Hospital Regional Cancer Center

BJU International
Timothy R AsmisShawn Malone

Abstract

To review patients with genitourinary (GU) small cell carcinoma (SCC) treated at a regional cancer centre, as due to its rarity and aggressive nature, GU SCC remains a therapeutic challenge. The charts of patients managed at a regional cancer centre between 1991 and 2002 for any GU diagnosis were manually reviewed to identify GU SCC. Demographic, staging, treatment and outcome data were extracted. The Veterans Administration small cell lung cancer staging classification of "limited" or "extensive" disease was adapted for SCC of the prostate and bladder (with "limited" defined as disease localized to the true and false pelvis, and "extensive" as disease beyond the pelvis). In all, 555, 858 and 5066 new cases of primary renal, bladder and prostate cancer, respectively, were identified. Of these patients, 22 had GU SCC (12 bladder and 10 prostate; there were no cases of SCC of the kidney). Eight of 12 patients with bladder SCC had limited disease; five of 12 are alive (all with limited disease at diagnosis), and the median survival was 19.8 months. Surviving patients received similar therapy, with transurethral resection of the bladder tumour, platinum-based chemotherapy, etoposide (4-6 cycles), and radical radiotherapy (56-60 Gy)...Continue Reading

References

Oct 15, 1984·Cancer·N B IbrahimC M Corbishley
Nov 1, 1995·Urology·F AbbasM S Soloway
Jul 16, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christos N PapandreouChristopher J Logothetis
Jan 16, 2003·Chest·George R SimonUNKNOWN American College of Chest Physicians

❮ Previous
Next ❯

Citations

May 9, 2008·International Journal of Clinical Oncology·Manabu KatouYoshiki Sugimura
Feb 25, 2011·International Journal of Clinical Oncology·Jonathan Edward BrammerGarrett Rush Lynch
Apr 30, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A BexS Horenblas
Apr 15, 2008·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Yesim YildirimBulent Celasun
Apr 9, 2011·Case Reports in Oncology·Antonio CapizzelloPeriklis Tsekeris
May 27, 2009·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Nabil IsmailiJean Pierre Droz
Dec 2, 2011·Archives of Pathology & Laboratory Medicine·Ross J MillerSubodh M Lele
Mar 28, 2013·Case Reports in Urology·Abdullah DemirtaşAtila Tatlışen
Jun 3, 2014·Journal of Medical Case Reports·Kursat CecenRamazan Kocaaslan
May 7, 2014·Prostate Cancer and Prostatic Diseases·P SargosA Fléchon
Oct 15, 2013·International Journal of Clinical Oncology·Jonathan Edward BrammerGarrett Rushing Lynch
Mar 19, 2014·Current Medical Research and Opinion·Ozan YazıcıNurullah Zengin
May 11, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·L T MacedoO De Cobelli
Dec 11, 2008·Cancer Treatment Reviews·Annemiek M E WalenkampDirk T Sleijfer
Feb 19, 2016·Current Medical Research and Opinion·Gökmen Umut ErdemNurullah Zengin
Mar 18, 2008·Urology·Aleksandra CiszewskiTomasz M Beer
Feb 13, 2015·Future Oncology·Kashyap ShatagopamMichael O Koch
Oct 25, 2017·Der Urologe. Ausg. A·S TritschlerM Hentrich
Jun 28, 2018·Der Pathologe·S TritschlerM Hentrich
Jan 2, 2016·Proceedings·Pamela HoofAdam Mora

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.