Genome Analysis of Conserved Dehydrin Motifs in Vascular Plants

Frontiers in Plant Science
Ahmad A MalikSteffen P Graether

Abstract

Dehydrins, a large family of abiotic stress proteins, are defined by the presence of a mostly conserved motif known as the K-segment, and may also contain two other conserved motifs known as the Y-segment and S-segment. Using the dehydrin literature, we developed a sequence motif definition of the K-segment, which we used to create a large dataset of dehydrin sequences by searching the Pfam00257 dehydrin dataset and the Phytozome 10 sequences of vascular plants. A comprehensive analysis of these sequences reveals that lysine residues are highly conserved in the K-segment, while the amino acid type is often conserved at other positions. Despite the Y-segment name, the central tyrosine is somewhat conserved, but can be substituted with two other small aromatic amino acids (phenylalanine or histidine). The S-segment contains a series of serine residues, but in some proteins is also preceded by a conserved LHR sequence. In many dehydrins containing all three of these motifs the S-segment is linked to the K-segment by a GXGGRRKK motif (where X can be any amino acid), suggesting a functional linkage between these two motifs. An analysis of the sequences shows that the dehydrin architecture and several biochemical properties (isoelect...Continue Reading

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Citations

Feb 7, 2019·PloS One·Andrew C RileySteffen P Graether
Nov 9, 2018·Genome Biology and Evolution·Mariana Aline Silva ArturHenk W M Hilhorst
Nov 6, 2018·International Journal of Molecular Sciences·Zhengyang YuLinsheng Zhang
Apr 4, 2019·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Manu PriyaHarsh Nayyar
Jun 27, 2017·Frontiers in Plant Science·Yang LiuDequan Li
Nov 18, 2018·Functional & Integrative Genomics·Sergio GálvezPilar Hernandez
May 19, 2019·Protein Science : a Publication of the Protein Society·Sharall R PalmerSteffen P Graether
May 7, 2019·Frontiers in Plant Science·Ana Paula Zotta MotaAna Cristina Miranda Brasileiro
Oct 6, 2020·Plant Signaling & Behavior·Xiaoyu WangLinsheng Zhang
Dec 15, 2020·Plant Physiology and Biochemistry : PPB·María Vazquez-HernandezMaría Isabel Escribano
Jan 22, 2021·Protein Science : a Publication of the Protein Society·Karamjeet K Singh, Steffen P Graether
Feb 13, 2021·International Journal of Molecular Sciences·Xuechun WangYing Gai
Oct 10, 2018·Biophysical Journal·Luisa A FerreiraSteffen P Graether
Jun 1, 2021·Plant Cell Reports·Riyazuddin RiyazuddinRavi Gupta

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Methods Mentioned

BETA
circular
NMR
dissection

Software Mentioned

R plot
EXPASY
SPSS Statistics
CATPCA
Genevestigator
LOGO
MEME
MAST
FoldIndex
BLASTP

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