Genome analysis technologies: towards species identification by genotype

Briefings in Functional Genomics & Proteomics
Mohammed Naimuddin, Koichi Nishigaki

Abstract

Traditional identification of species has been based on phenotypic traits, although it is clear that, theoretically, genotype-based classification is more accurate. This is especially the case for microorganisms which possess less identifiable traits and are more easily influenced by environment. Therefore, technology that allows identification of species based on genotype is highly desirable. Whole genome sequencing can provide a sufficient amount of information and can be determinative for this purpose but is very impractical for routine use. Thus, a competent technology is needed that allows a reproducible reduction in the amount of information required about a whole genome, while still providing sufficiently accurate identification. It is almost imperative for such a technology to be of a high cost-performance and of easy handling. Universality and portability are also strongly desired. Based on these criteria, the current state of genome analysis technologies are reviewed. Among various methodologies discussed here, amplified fragment length polymorphism (AFLP), genome profiling (GP) and microarrays are the subject of particular attention. As species identification is a base for most fields of biology including microbiolog...Continue Reading

Citations

Mar 10, 2012·Journal of Microbiological Methods·Keiichi HamanoKoichi Nishigaki
Feb 7, 2008·International Journal of Plant Genomics·Mariko KoudukaKoichi Nishigaki
Sep 26, 2013·Gut Pathogens·Stefan R HerbelSebastian Guenther
Feb 20, 2014·BMC Genomics·Deepti DiwanKoichi Nishigaki
Mar 28, 2007·Heart Failure Clinics·Neil E BowlesJeffrey A Towbin
Feb 7, 2006·Veterinary Parasitology·Robin B Gasser

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