PMID: 8994839Dec 1, 1996Paper

Genome research and evolution in trypanosomes

Current Opinion in Genetics & Development
J E Donelson

Abstract

Trypanosoma brucei and Trypanosoma cruzi cause different human diseases. As strategies for immune evasion, T. brucei undergone antigenic variation whereas T. cruzi becomes an intracellular organism. This fundamental difference is reflected by major differences in their genome organizations. Recent comparisons of their gene sequences indicate that these two trypanosome species are highly divergent evolutionarily.

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Citations

Mar 25, 2000·International Journal for Parasitology·N M El-SayedJ E Donelson
May 9, 1998·Molecular and Biochemical Parasitology·J HaagP Overath
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Nov 3, 2010·IEEE Transactions on Visualization and Computer Graphics·Steven Henderson, Steven Feiner
Jan 6, 2001·Memórias do Instituto Oswaldo Cruz·D G Colley

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