Genome sequence analysis of a novel Enterobacter cloacae phage, Ec_L1, belonging to the genus Eclunavirus

Archives of Virology
Hongyu RenYongping Xu

Abstract

Phages, viruses targeting bacteria, have potential therapeutic applications in the control of infections with antibiotic-resistant bacteria. In this study, an Enterobacter cloacae phage, Ec_L1, was isolated from sewage sludge samples collected from a hospital. The genome of phage Ec_L1 consists of 51,894 bp with 48.24% G+C content. Nineteen of the 85 putative proteins encoded by this phage have known functions, and no rRNA or tRNA genes were found. Comparative analysis of genome sequences suggested that phage Ec_L1 should be considered a member of the subfamily Tunavirinae, which includes T1-like phages. According to the International Committee on Taxonomy of Viruses (ICTV), phage Ec_L1 is the type member of the new genus "Eclunavirus", whose name was derived from Ec_L1.

References

Apr 1, 1997·Clinical Microbiology Reviews·W E Sanders, C C Sanders
Jul 26, 2012·Future Microbiology·Maria Lina MezzatestaStefania Stefani
Aug 31, 2016·Nature Microbiology·Victor I BandDavid S Weiss
Apr 19, 2017·Emerging Infectious Diseases·Brigid M WilsonFederico Perez
Feb 16, 2019·Frontiers in Microbiology·Medini K AnnavajhalaAnne-Catrin Uhlemann

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Datasets Mentioned

BETA
KJ101592
MG999954

Software Mentioned

BLASTp
BLAST
MEGA
BLASTx
ARAGORN

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