Genome-Wide Association Mapping of Correlated Traits in Cassava: Dry Matter and Total Carotenoid Content

The Plant Genome
Ismail Y RabbiPeter Kulakow

Abstract

Cassava is a starchy root crop cultivated in the tropics for fresh consumption and commercial processing. Primary selection objectives in cassava breeding include dry matter content and micronutrient density, particularly provitamin A carotenoids. These traits are negatively correlated in the African germplasm. This study aimed at identifying genetic markers associated with these traits and uncovering whether linkage and/or pleiotropy were responsible for observed negative correlation. A genome-wide association mapping using 672 clones genotyped at 72,279 single nucleotide polymorphism (SNP) loci was performed. Root yellowness was used indirectly to assess variation in carotenoid content. Two major loci for root yellowness were identified on chromosome 1 at positions 24.1 and 30.5 Mbp. A single locus for dry matter content that colocated with the 24.1 Mbp peak for carotenoids was identified. Haplotypes at these loci explained 70 and 37% of the phenotypic variability for root yellowness and dry matter content, respectively. Evidence of megabase-scale linkage disequilibrium (LD) around the major loci of the two traits and detection of the major dry matter locus in independent analysis for the white- and yellow-root subpopulations...Continue Reading

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Citations

Oct 17, 2018·Biopreservation and Biobanking·Michael HalewoodRuaraidh Sackville Hamilton
Jan 26, 2018·Scientific Reports·Siraj Ismail KayondoJean-Luc Jannink
May 16, 2020·Scientific Reports·Bilan Omar YonisIsmail Rabbi
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Jun 6, 2020·The Plant Journal : for Cell and Molecular Biology·Uwe SonnewaldWolfgang Zierer
Dec 29, 2020·Journal of Plant Physiology·Federico ScossaAlisdair R Fernie
Dec 22, 2020·Molecular Plant·Chu-Yu Ye, Longjiang Fan
Nov 30, 2019·Plant Science : an International Journal of Experimental Plant Biology·Tianhu Sun, Li Li
Feb 9, 2021·Frontiers in Genetics·Edwige Gaby Nkouaya MbanjoChiedozie Egesi
Feb 13, 2021·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Alex C OgbonnaGuillaume J Bauchet
Feb 20, 2021·Plant Molecular Biology·Jessica B LyonsRebecca S Bart

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Methods Mentioned

BETA
genotyping
Genetic

Software Mentioned

PLINK
TASSEL
Bowtie
R
lme4

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