Genome-wide association studies of family data in pharmacogenetics: a case study.

Current Pharmaceutical Design
Amy MurphyScott T Weiss

Abstract

Genome-wide associations studies (GWAS) have become routine in human genetics research; however the application of GWAS to pharmacogenomics research is just beginning. As these studies make their way into pharmacogenetics, there are several considerations specific to pharmacogenetics that should be made. In this manuscript, we discuss these considerations and provide concrete examples with GWAS data for an asthma clinical trial using parent-offspring trios.

Citations

Apr 28, 2012·American Journal of Respiratory and Critical Care Medicine·Kelan G TantisiraUNKNOWN SHARP Investigators

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