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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

Molecular Psychiatry

Sep 25, 2017

T-K ClarkeAndrew M McIntosh

Abstract

Alcohol consumption has been linked to over 200 diseases and is responsible for over 5% of the global disease burden. Well-known genetic variants in alcohol metabolizing genes, for example, ALDH2 and ADH1B, are strongly associated with alcohol consumption but have limited impact in Euro...read more

Mentioned in this Paper

Genome-Wide Association Study
PDE4B gene
Study
ADH1C
MAP4K5 gene
DRD2 protein, human
Alcohol Metabolism
Genome
Genes
Genetic Screening Method
35
1
167
Paper Details
References
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  • Citations42
1
  • References3
  • Citations42
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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

Molecular Psychiatry

Sep 25, 2017

T-K ClarkeAndrew M McIntosh

PMID: 28937693

DOI: 10.1038/mp.2017.153

Abstract

Alcohol consumption has been linked to over 200 diseases and is responsible for over 5% of the global disease burden. Well-known genetic variants in alcohol metabolizing genes, for example, ALDH2 and ADH1B, are strongly associated with alcohol consumption but have limited impact in Euro...read more

Mentioned in this Paper

Genome-Wide Association Study
PDE4B gene
Study
ADH1C
MAP4K5 gene
DRD2 protein, human
Alcohol Metabolism
Genome
Genes
Genetic Screening Method
35
1
167

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Cholesterol is essential for a variety of cellular processes, including cell growth and division, and it plays an important role in various signaling pathways. Here is the latest research on cholesterol synthesis and the role of cholesterol in cell signaling.

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Paper Details
References
  • References3
  • Citations42
1
  • References3
  • Citations42
12345

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