Genome-wide demethylation during neural differentiation of P19 embryonal carcinoma cells.

Journal of Human Genetics
I HatadaKenta Nakai

Abstract

Epigenetic regulation including DNA methylation plays an important role in several differentiation processes. We profiled global DNA methylation in the neural differentiation of P19 embryonic carcinoma cells using a microarray-based method called MIAMI. We found a genome-wide demethylation of genes. This suggests demethylation rather than methylation is important in neural differentiation.

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Citations

Aug 3, 2012·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Yasuko KobayashiHirokazu Arakawa
Mar 2, 2012·Nucleic Acids Research·Leonid Schneider, Fabrizio d'Adda di Fagagna
Nov 26, 2008·BMC Medical Genomics·Maté OngenaertEd Schuuring
Oct 1, 2009·Epigenomics·Judy Sng, Michael J Meaney
Dec 12, 2012·International Journal of Oncology·Osamu DohiToshikazu Yoshikawa
Dec 2, 2015·British Journal of Cancer·Hoi-Hung CheungWai-Yee Chan
Apr 5, 2017·Stem Cells International·Gregory M Kelly, Mohamed I Gatie
Dec 6, 2020·Scientific Reports·Kenichi KawahoriKoshi Hashimoto

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