journal cover

Genome-wide detection and characterization of positive selection in human populations

Nature

Oct 19, 2007

Pardis C SabetiJohn Stewart

Abstract

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' m...read more

Mentioned in this Paper

Heuristics
EDAR gene
Cation Exchange Proteins
SLC24A5 gene
Human Genetics
Tertiary Protein Structure
Genetics, Population
Sample Fixation
SLC24A5 protein, human
EDA2R gene
4
1
1534
1
2
Paper Details
References
  • References33
  • Citations641
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  • References33
  • Citations641
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Related Papers

Genome Research

Signals of recent positive selection in a worldwide sample of human populations

Genome ResearchMarch 25, 2009
Joseph K PickrellJonathan K Pritchard
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Genome-wide detection and characterization of positive selection in human populations

Nature

Oct 19, 2007

Pardis C SabetiJohn Stewart

PMID: 17943131

DOI: 10.1038/nature06250

Abstract

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' m...read more

Mentioned in this Paper

Heuristics
EDAR gene
Cation Exchange Proteins
SLC24A5 gene
Human Genetics
Tertiary Protein Structure
Genetics, Population
Sample Fixation
SLC24A5 protein, human
EDA2R gene
4
1
1534
1
2

Feeds With Similar Papers

International Cancer Genomics Consortium (ICGC)

The International Cancer Genomics Consortium (ICGC) was established to investigate the genomic changes present in many forms of cancer. Follow this feed to stay up to date on research from this institute.

Viral Hemorrhagic Fevers

Viral Hemorrhagic Fevers caused by ebola, marburg and lassa viruses often manifest as multiple organ dysfunction and hemorrhagic shock with high mortality. Discover the latest research on Viral Hemorrhagic Fevers here.

Related Papers

Genome Research

Signals of recent positive selection in a worldwide sample of human populations

Genome ResearchMarch 25, 2009
Joseph K PickrellJonathan K Pritchard
Paper Details
References
  • References33
  • Citations641
1234
  • References33
  • Citations641
12345...

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