Genome-wide mapping of 10 calving and fertility traits in Holstein dairy cattle with special regard to chromosome 18

Journal of Dairy Science
M-P MüllerIvica Medugorac

Abstract

Over the last decades, a dramatic decrease in reproductive performance has been observed in Holstein cattle and fertility problems have become the most common reason for a cow to leave the herd. The premature removal of animals with high breeding values results in both economic and breeding losses. For efficient future Holstein breeding, the identification of loci associated with low fertility is of major interest and thus constitutes the aim of this study. To reach this aim, a genome-wide combined linkage disequilibrium and linkage analysis (cLDLA) was conducted using data on the following 10 calving and fertility traits in the form of estimated breeding values: days from first service to conception of heifers and cows, nonreturn rate on d 56 of heifers and cows, days from calving to first insemination, days open, paternal and maternal calving ease, paternal and maternal stillbirth. The animal data set contained 2,527 daughter-proven Holstein bulls from Germany that were genotyped with Illumina's BovineSNP50 BeadChip (Illumina Inc., San Diego, CA). For the cLDLA, 41,635 sliding windows of 40 adjacent single nucleotide polymorphisms (SNP) were used. At each window midpoint, a variance component analysis was executed using ASRem...Continue Reading

References

May 1, 1975·Journal of Animal Science·J J Rutledge
Jul 1, 1984·Journal of Dairy Science·B R MangurkarJ E Moxley
Nov 1, 1981·Journal of Animal Science·P J BurfeningR L Friedrich
Sep 26, 2000·Mammalian Genome : Official Journal of the International Mammalian Genome Society·S LienL Gomez-Raya
Dec 18, 2001·Genetics, Selection, Evolution : GSE·T H E Meuwissen, M E Goddard
Apr 15, 2004·Behavior Genetics·Peter M Visscher, Mike E Goddard
Apr 27, 2004·Genetics, Selection, Evolution : GSE·T H E Meuwissen, Mike E Goddard
May 21, 2005·Journal of Dairy Science·J JamrozikL R Schaeffer
Aug 11, 2006·Journal of Dairy Science·M Holmberg, L Andersson-Eklund
Nov 14, 2006·The Veterinary Record·J N Huxley, H R Whay
Feb 20, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·B-A TenhagenW Heuwieser
Nov 21, 2007·The Veterinary Record·B J McGuirkH Dobson
Mar 11, 2008·The Veterinary Journal·J F Mee
Apr 19, 2008·Journal of Dairy Science·J R ThomasenMogens S Lund
Feb 10, 2009·American Journal of Human Genetics·Brian L Browning, Sharon R Browning
May 7, 2009·Annals of the New York Academy of Sciences·Barbara M C McGowanStephen R Bloom
May 19, 2009·Journal of Dairy Science·J B ColeGeorge R Wiggans
Aug 29, 2009·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Emma Cooke, Veronica James
Nov 17, 2009·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·T SeidenspinnerG Thaller
Sep 30, 2010·Nature Reviews. Genetics·Joseph E PowellMichael E Goddard
Dec 25, 2010·Journal of Dairy Science·Goutam SahanaMogens S Lund
Jan 25, 2011·Animal Reproduction Science·S W WalshA C O Evans
Mar 26, 2011·The American Journal of Pathology·Ie-Ming ShihTian-Li Wang
Jun 28, 2012·PloS One·Ivica MedugoracStefan Krebs
Aug 15, 2012·BMC Genetics·Johanna K HöglundGoutam Sahana
Sep 1, 1992·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·J W van Ooijen
Nov 22, 2013·Animal : an International Journal of Animal Bioscience·D C PurfieldD P Berry
Jan 30, 2014·Nature Genetics·Jian YangAlkes L Price
Nov 2, 2014·Genetics, Selection, Evolution : GSE·Sophie RothammerArmin M Scholz
Feb 6, 2015·Genetics, Selection, Evolution : GSE·Stefano BiffaniFilippo Biscarini
Mar 20, 2016·Genetics, Selection, Evolution : GSE·Elisabeth KunzIvica Medugorac
Jul 21, 2017·American Journal of Public Health·Alexis Dinno

Citations

Apr 22, 2018·The Veterinary Record·Victoria GoeckmannIvica Medugorac
Jul 6, 2017·Genetics, Selection, Evolution : GSE·Serap GonenJohn M Hickey
Jul 8, 2018·Genetics, Selection, Evolution : GSE·Sophie RothammerIvica Medugorac
Feb 9, 2020·Genetics, Selection, Evolution : GSE·Lilian Johanna GehrkeG Thaller
Mar 8, 2021·Genetics, Selection, Evolution : GSE·Christin SchmidtmannG Thaller

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