Genome-wide mapping of 10 calving and fertility traits in Holstein dairy cattle with special regard to chromosome 18

Journal of Dairy Science
M-P MüllerIvica Medugorac


Over the last decades, a dramatic decrease in reproductive performance has been observed in Holstein cattle and fertility problems have become the most common reason for a cow to leave the herd. The premature removal of animals with high breeding values results in both economic and breeding losses. For efficient future Holstein breeding, the identification of loci associated with low fertility is of major interest and thus constitutes the aim of this study. To reach this aim, a genome-wide combined linkage disequilibrium and linkage analysis (cLDLA) was conducted using data on the following 10 calving and fertility traits in the form of estimated breeding values: days from first service to conception of heifers and cows, nonreturn rate on d 56 of heifers and cows, days from calving to first insemination, days open, paternal and maternal calving ease, paternal and maternal stillbirth. The animal data set contained 2,527 daughter-proven Holstein bulls from Germany that were genotyped with Illumina's BovineSNP50 BeadChip (Illumina Inc., San Diego, CA). For the cLDLA, 41,635 sliding windows of 40 adjacent single nucleotide polymorphisms (SNP) were used. At each window midpoint, a variance component analysis was executed using ASRem...Continue Reading


May 1, 1975·Journal of Animal Science·J J Rutledge
Jul 1, 1984·Journal of Dairy Science·B R MangurkarJ E Moxley
Nov 1, 1981·Journal of Animal Science·P J BurfeningR L Friedrich
Sep 26, 2000·Mammalian Genome : Official Journal of the International Mammalian Genome Society·S LienL Gomez-Raya
Dec 18, 2001·Genetics, Selection, Evolution : GSE·T H E Meuwissen, M E Goddard
Apr 15, 2004·Behavior Genetics·Peter M Visscher, Mike E Goddard
Apr 27, 2004·Genetics, Selection, Evolution : GSE·T H E Meuwissen, Mike E Goddard
May 21, 2005·Journal of Dairy Science·J JamrozikL R Schaeffer
Aug 11, 2006·Journal of Dairy Science·M Holmberg, L Andersson-Eklund
Nov 14, 2006·The Veterinary Record·J N Huxley, H R Whay
Feb 20, 2007·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·B-A TenhagenW Heuwieser
Nov 21, 2007·The Veterinary Record·B J McGuirkH Dobson
Mar 11, 2008·The Veterinary Journal·J F Mee
Apr 19, 2008·Journal of Dairy Science·J R ThomasenMogens S Lund
Feb 10, 2009·American Journal of Human Genetics·Brian L Browning, Sharon R Browning
May 7, 2009·Annals of the New York Academy of Sciences·Barbara M C McGowanStephen R Bloom
May 19, 2009·Journal of Dairy Science·J B ColeGeorge R Wiggans
Aug 29, 2009·Journal of Child Health Care : for Professionals Working with Children in the Hospital and Community·Emma Cooke, Veronica James
Nov 17, 2009·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·T SeidenspinnerG Thaller
Sep 30, 2010·Nature Reviews. Genetics·Joseph E PowellMichael E Goddard
Dec 25, 2010·Journal of Dairy Science·Goutam SahanaMogens S Lund
Jan 25, 2011·Animal Reproduction Science·S W WalshA C O Evans
Mar 26, 2011·The American Journal of Pathology·Ie-Ming ShihTian-Li Wang
Jun 28, 2012·PloS One·Ivica MedugoracStefan Krebs
Aug 15, 2012·BMC Genetics·Johanna K HöglundGoutam Sahana
Sep 1, 1992·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·J W van Ooijen
Nov 22, 2013·Animal : an International Journal of Animal Bioscience·D C PurfieldD P Berry
Jan 30, 2014·Nature Genetics·Jian YangAlkes L Price
Nov 2, 2014·Genetics, Selection, Evolution : GSE·Sophie RothammerArmin M Scholz
Feb 6, 2015·Genetics, Selection, Evolution : GSE·Stefano BiffaniFilippo Biscarini
Mar 20, 2016·Genetics, Selection, Evolution : GSE·Elisabeth KunzIvica Medugorac
Jul 21, 2017·American Journal of Public Health·Alexis Dinno


Apr 22, 2018·The Veterinary Record·Victoria GoeckmannIvica Medugorac
Jul 6, 2017·Genetics, Selection, Evolution : GSE·Serap GonenJohn M Hickey
Jul 8, 2018·Genetics, Selection, Evolution : GSE·Sophie RothammerIvica Medugorac
Feb 9, 2020·Genetics, Selection, Evolution : GSE·Lilian Johanna GehrkeG Thaller
Mar 8, 2021·Genetics, Selection, Evolution : GSE·Christin SchmidtmannG Thaller

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.