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Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity

Nature Methods

Nov 21, 2019

Shalom Hillel RothEli Eisenberg

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Abstract

Adenosine-to-inosine (A-to-I) RNA editing by the adenosine deaminase that acts on RNA (ADAR) enzymes is a common RNA modification, preventing false activation of the innate immune system by endogenous double-stranded RNAs. Methods for quantification of ADAR activity are sought after, du...read more

Mentioned in this Paper

Adenosine
Adenosine Deaminase
Autoimmune Diseases
Malignant Neoplasms
RNA
RNA, Double-Stranded
Tissue Engineering
Comparative Study Research
Genome-Wide Association Study
Adar protein, Drosophila
9
1
31
1
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Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity

Nature Methods

Nov 21, 2019

Shalom Hillel RothEli Eisenberg

PMID: 31636457

DOI: 10.1038/s41592-019-0610-9

Abstract

Adenosine-to-inosine (A-to-I) RNA editing by the adenosine deaminase that acts on RNA (ADAR) enzymes is a common RNA modification, preventing false activation of the innate immune system by endogenous double-stranded RNAs. Methods for quantification of ADAR activity are sought after, du...read more

Mentioned in this Paper

Adenosine
Adenosine Deaminase
Autoimmune Diseases
Malignant Neoplasms
RNA
9
1
31
1

Similar Papers Found In These Feeds

Paper Details
References
  • References66
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.

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