Genomic analysis of the histidine kinase family in bacteria and archaea

Microbiology
D Kim, S Forst

Abstract

Two-component signal transduction systems, consisting of histidine kinase (HK) sensors and DNA-binding response regulators, allow bacteria and archaea to respond to diverse environmental stimuli. HKs possess a conserved domain (H-box region) which contains the site of phosphorylation and an ATP-binding kinase domain. In this study, a genomic approach was taken to analyse the HK family in bacteria and archaea. Based on phylogenetic analysis, differences in the sequence and organization of the H-box and kinase domains, and the predicted secondary structure of the H-box region, five major HK types were identified. Of the 336 HKs analysed, 92% could be assigned to one of the five major HK types. The Type I HKs were found predominantly in bacteria while Type II HKs were not prevalent in bacteria but constituted the major type (13 of 15 HKs) in the archaeon Archaeoglobus fulgidus. Type III HKs were generally more prevalent in Gram-positive bacteria and were the major HK type (14 of 15 HKs) in the archaeon Methanobacterium thermoautotrophicum. Type IV HKs represented a minor type found in bacteria. The fifth HK type was composed of the chemosensor HKs, CheA. Several bacterial genomes contained all five HK types. In contrast, archaeal ...Continue Reading

References

Jan 1, 1992·Annual Review of Genetics·J S Parkinson, E C Kofoid
Jul 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·E C Kofoid, J S Parkinson
Jun 1, 1994·Research in Microbiology·S A Forst, D L Roberts
Oct 22, 1993·Science·I M Ota, A Varshavsky
Apr 16, 1996·Proceedings of the National Academy of Sciences of the United States of America·L A AlexM I Simon
Dec 31, 1996·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·T MizunoS Tabata
Mar 1, 1997·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·L A EggerM Inouye
Apr 28, 1997·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·T Mizuno
Sep 5, 1997·Science·F R BlattnerY Shao
Feb 19, 1998·Nature·K Davies
Jun 17, 1998·Proceedings of the National Academy of Sciences of the United States of America·H ParkM Inouye
Jul 29, 1998·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Y KawarabayasiH Kikuchi
Feb 16, 1999·Cell·A M BilwesM I Simon
Mar 6, 1999·Current Opinion in Microbiology·W F LoomisG Shaulsky
Apr 21, 1999·Trends in Microbiology·A L PerraudR Gross
Jun 16, 1999·Structure·V L Robinson, A M Stock
Jun 26, 1999·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Y KawarabayasiH Kikuchi
Sep 29, 1999·Advances in Microbial Physiology·T W Grebe, J B Stock
Nov 24, 1999·Molecular Microbiology·R DuttaM Inouye
Oct 4, 2000·Proceedings of the National Academy of Sciences of the United States of America·W V NgS DasSarma

❮ Previous
Next ❯

Citations

Feb 7, 2016·Journal of Molecular Biology·Jimena RinaldiFernando Alberto Goldbaum
Jan 15, 2008·The FEBS Journal·Abid R MattooYogendra Singh
May 20, 2015·Structure·Manasi P BhateWilliam F DeGrado
Jan 15, 2015·Molecular Microbiology·Allison N Norsworthy, Karen L Visick
Aug 27, 2013·Microbiological Research·Amrathlal Rabbind SinghKuppamuthu Dharmalingam
Feb 27, 2010·Journal of Molecular Biology·Stanislaw Dunin-Horkawicz, Andrei N Lupas
Nov 22, 2012·FEMS Microbiology Reviews·Jerry Eichler, Julie Maupin-Furlow
Jul 8, 2014·Frontiers in Cellular and Infection Microbiology·Yuta OkkotsuMichael J Schurr
May 29, 2016·Environmental Microbiology·Adrian F AlvarezDimitris Georgellis
Jul 4, 2012·Annual Review of Microbiology·Emily J Capra, Michael T Laub
Apr 8, 2003·Proceedings of the National Academy of Sciences of the United States of America·Lewyn LiLeonid A Mirny
Jun 15, 2011·Proceedings of the National Academy of Sciences of the United States of America·Ji-Young SongYoun-Il Park
Feb 27, 2003·Proceedings of the National Academy of Sciences of the United States of America·Baruch Karniol, Richard D Vierstra
Jan 11, 2008·Molecular Plant-microbe Interactions : MPMI·Wei QianChaozu He
Jan 27, 2009·The Journal of Antibiotics·Hum Nath JnawaliJae Kyung Sohng
Dec 1, 2011·Microbiology and Molecular Biology Reviews : MMBR·Daniel J BretlThomas C Zahrt
Feb 11, 2014·Applied and Environmental Microbiology·Sergio RicoMargarita Díaz
Sep 27, 2018·Genome Biology and Evolution·Samar KabbaraNicolas Papon
Feb 26, 2009·Amino Acids·David E Whitworth, Peter J A Cock
Mar 7, 2007·Science Progress·Martijn BekkerKlaas J Hellingwerf
Feb 11, 2005·Journal of Biomolecular Structure & Dynamics·Debashis Mukhopadhyay, Kottayil I Varughese
May 10, 2013·Applied Biochemistry and Biotechnology·Amit Kumar BanerjeeBatepatti Karuna
Jan 10, 2017·Frontiers in Microbiology·Richard L HahnkeMarkus Göker
May 13, 2014·Microbiology·Denina HospodskyJordan Peccia

❮ Previous
Next ❯

Related Concepts

Related Feeds

Archaeogenetics

Recent advances in genomic sequencing has led to the discovery of new strains of Archaea and shed light on their evolutionary history. Discover the latest research on Archaeogenetics here.