Genomic consequences of dietary diversification and parallel evolution due to nectarivory in leaf-nosed bats.

GigaScience
Yocelyn T Gutiérrez-GuerreroLuis E Eguiarte

Abstract

The New World leaf-nosed bats (Phyllostomids) exhibit a diverse spectrum of feeding habits and innovations in their nutrient acquisition and foraging mechanisms. However, the genomic signatures associated with their distinct diets are unknown. We conducted a genomic comparative analysis to study the evolutionary dynamics related to dietary diversification and specialization. We sequenced, assembled, and annotated the genomes of five Phyllostomid species: one insect feeder (Macrotus waterhousii), one fruit feeder (Artibeus jamaicensis), and three nectar feeders from the Glossophaginae subfamily (Leptonycteris yerbabuenae, Leptonycteris nivalis, and Musonycteris harrisoni), also including the previously sequenced vampire Desmodus rotundus. Our phylogenomic analysis based on 22,388 gene families displayed differences in expansion and contraction events across the Phyllostomid lineages. Independently of diet, genes relevant for feeding strategies and food intake experienced multiple expansions and signatures of positive selection. We also found adaptation signatures associated with specialized diets: the vampire exhibited traits associated with a blood diet (i.e., coagulation mechanisms), whereas the nectarivore clade shares a grou...Continue Reading

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Citations

Aug 17, 2020·ELife·Chaitanya A KulkarniPaul S Brookes
Feb 16, 2021·Molecular Biology and Evolution·Joshua H T PotterStephen J Rossiter
Aug 25, 2021·Molecular Biology and Evolution·Joshua H T PotterStephen J Rossiter
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Jun 20, 2021·Molecular Ecology·Diana D Moreno SantillánLiliana M Dávalos

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Datasets Mentioned

BETA
PRJNA542899
SRR9076597
PRJNA543325

Methods Mentioned

BETA
glycosylation
GTPase
RNA-Seq

Key Resources (RRID) Mentioned

SCR_015531
SCR_014731
SCR_015008
SCR_012954
SCR_013048
SCR_008417
SCR_001876
SCR_010910
SCR_006525
SCR_005829

Software Mentioned

Genome Analysis Toolkit
RealignerTargetCreator
BCFtools
MCMCtree
HaplotypeCaller
DIAMOND
MAFFT
SAMtools
CODEML
Basic Local Alignment Search Tool Aligner

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