Genomic diversity within the Enterobacter cloacae complex.

PloS One
Armand PaauwAd C Fluit

Abstract

Isolates of the Enterobacter cloacae complex have been increasingly isolated as nosocomial pathogens, but phenotypic identification of the E. cloacae complex is unreliable and irreproducible. Identification of species based on currently available genotyping tools is already superior to phenotypic identification, but the taxonomy of isolates belonging to this complex is cumbersome. This study shows that multilocus sequence analysis and comparative genomic hybridization based on a mixed genome array is a powerful method for studying species assignment within the E. cloacae complex. The E. cloacae complex is shown to be evolutionarily divided into two clades that are genetically distinct from each other. The younger first clade is genetically more homogenous, contains the Enterobacter hormaechei species and is the most frequently cultured Enterobacter species in hospitals. The second and older clade consists of several (sub)species that are genetically more heterogeneous. Genetic markers were identified that could discriminate between the two clades and cluster 1. Based on genomic differences it is concluded that some previously defined (clonal and heterogenic) (sub)species of the E. cloacae complex have to be redefined because of...Continue Reading

References

Dec 20, 2000·Proceedings of the National Academy of Sciences of the United States of America·N SalamaS Falkow
Jul 12, 2001·Proceedings of the National Academy of Sciences of the United States of America·J R FitzgeraldJ M Musser
Sep 7, 2001·Annual Review of Microbiology·E J Feil, B G Spratt
Nov 29, 2001·Proceedings of the National Academy of Sciences of the United States of America·D A IsraelR M Peek
Jun 20, 2002·Proceedings of the National Academy of Sciences of the United States of America·Steffen PorwollikMichael McClelland
Nov 26, 2002·Molecular Biology and Evolution·Sebastian E Ramos-Onsins, Julio Rozas
Sep 6, 2003·Applied and Environmental Microbiology·Harald Hoffmann, Andreas Roggenkamp
Dec 12, 2003·Bioinformatics·Julio RozasRicardo Rozas
Dec 8, 2004·FEBS Letters·Hari S MisraShree K Apte
Dec 23, 2004·Systematic and Applied Microbiology·André MehlenKarl-Heinz Schleifer
May 20, 2005·Systematic and Applied Microbiology·Harald HoffmannAndreas Roggenkamp
Oct 14, 2005·Molecular Biology and Evolution·Daniel H Huson, David Bryant
May 18, 2006·Emerging Infectious Diseases·Armand PaauwMaurine A Leverstein-van Hall
Oct 31, 2006·Applied and Environmental Microbiology·Rebecca J CaseStaffan Kjelleberg
Dec 8, 2006·Genetics·Xavier Didelot, Daniel Falush
Sep 18, 2007·International Journal of Hygiene and Environmental Health·Peter KämpferMichael Esser
Sep 27, 2007·Genome Research·Thierry WirthMark Achtman

❮ Previous
Next ❯

Citations

Jul 26, 2012·Future Microbiology·Maria Lina MezzatestaStefania Stefani
Jul 12, 2014·Analytical Chemistry·Ahmed M HamidR Graham Cooks
Sep 10, 2014·Standards in Genomic Sciences·Jodi L HumannBrenda K Schroeder
Jun 12, 2009·Journal of Clinical Microbiology·Philippe C MorandValérie Dumaine
Nov 17, 2009·BMC Genomics·Neeltje CarpaijRob Jl Willems
Dec 4, 2009·Journal of Clinical Microbiology·Albertine LeonRoland Leclercq
Sep 27, 2013·PloS One·Wing-Yee LiuFrederick Chi-Ching Leung
Oct 4, 2013·Journal of Clinical Microbiology·Sylvain BrisseDominique Decré
Dec 20, 2011·Standards in Genomic Sciences·Kristen M DeangelisTerry C Hazen
Jun 8, 2012·Standards in Genomic Sciences·Jodi L HumannBrenda K Schroeder
Sep 29, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F SzabadosG Geis
Jun 1, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A Kremer, H Hoffmann
Jul 3, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S S RichterG W Procop
Apr 3, 2012·Veterinary Microbiology·T AbaynehH Sørum
May 11, 2010·Microbial Pathogenesis·Sylwia KrzymińskaAdam Kaznowski
Aug 8, 2014·Journal of Microbiological Methods·Marre van den BrandMartine P Bos
Mar 10, 2015·International Journal of Systematic and Evolutionary Microbiology·Anne Le Flèche-MatéosJean-Claude Manuguerra
Sep 14, 2014·The Journal of Antimicrobial Chemotherapy·R IzdebskiUNKNOWN MOSAR WP2, WP3 and WP5 Study Groups
Jun 19, 2013·PloS One·Tohru Miyoshi-AkiyamaTeruo Kirikae
Jul 7, 2016·The Journal of Antibiotics·Thais Bergamin LimaOctávio Luiz Franco
Jun 24, 2017·Natural Product Reports·Andrew M Gulick
Oct 7, 2015·Antimicrobial Agents and Chemotherapy·François GuérinJean Christophe Giard
Jul 19, 2019·Clinical Microbiology Reviews·Anne Davin-RegliJean-Marie Pagès
Apr 17, 2019·Journal of Food and Drug Analysis·Tsung-Yun HouShih-Hua Teng
Dec 12, 2018·Microbiology Resource Announcements·Christopher R DumiganManish N Raizada
Jun 10, 2019·Environmental Monitoring and Assessment·Veronica Fernandes, Kalisa Bogati

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Methods Mentioned

BETA
genotyping
PCR
PCA
Electrophoresis

Software Mentioned

CGH
DNAsp
BioEdit
DAMBE
seqboot
GACK
MLSA
TIGR MeV
Pars
ImaGene

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