Genomic evidence for intraspecific hybridization in a clonal and extremely halotolerant yeast

BMC Genomics
Cene GostinčarNina Gunde-Cimerman

Abstract

The black yeast Hortaea werneckii (Dothideomycetes, Ascomycota) is one of the most extremely halotolerant fungi, capable of growth at NaCl concentrations close to saturation. Although dothideomycetous fungi are typically haploid, the reference H. werneckii strain has a diploid genome consisting of two subgenomes with a high level of heterozygosity. In order to explain the origin of the H. werneckii diploid genome we here report the genome sequencing of eleven strains isolated from different habitats and geographic locations. Comparison of nine diploid and two haploid strains showed that the reference genome was likely formed by hybridization between two haploids and not by endoreduplication as suggested previously. Results also support additional hybridization events in the evolutionary history of investigated strains, however exchange of genetic material in the species otherwise appears to be rare. Possible links between such unusual reproduction and the extremotolerance of H. werneckii remain to be investigated. H. werneckii appears to be able to form persistent haploid as well as diploid strains, is capable of occasional hybridization between relatively heterozygous haploids, but is otherwise limited to clonal reproduction. ...Continue Reading

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Citations

Jun 7, 2019·Genes·Xiaohuan SunNina Gunde-Cimerman
May 22, 2019·Environmental Microbiology·Cene GostinčarNina Gunde-Cimerman
Jan 23, 2020·Genes·Himeshi SamarasingheTimothy Y James
Apr 18, 2020·Biological Reviews of the Cambridge Philosophical Society·Miguel A Naranjo-Ortiz, Toni Gabaldón
Jul 15, 2020·Annual Review of Microbiology·Timothy Y JamesAntonis Rokas
Mar 7, 2018·Genes·Cene Gostinčar, Nina Gunde-Cimerman
Sep 26, 2019·Frontiers in Microbiology·Cene GostinčarZewei Song
Nov 25, 2020·Mycologia·Claudia ColeineLaura Selbmann
Oct 15, 2019·Current Biology : CB·Lorna M Y Mitchison-FieldAmy S Gladfelter
Oct 30, 2020·Journal of Fungi·Cene Gostinčar

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Datasets Mentioned

BETA
PRJNA428320

Software Mentioned

nucmer
IDBA
QIIME
R package phangorn
Augustus
ETE Toolkit
PhyML
samtools
MAKER
Mummer

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