Genomic evidence for role of inversion 3RP of Drosophila melanogaster in facilitating climate change adaptation

Molecular Ecology
Rahul V RaneAry A Hoffmann

Abstract

Chromosomal inversion polymorphisms are common in animals and plants, and recent models suggest that alternative arrangements spread by capturing different combinations of alleles acting additively or epistatically to favour local adaptation. It is also thought that inversions typically maintain favoured combinations for a long time by suppressing recombination between alternative chromosomal arrangements. Here, we consider patterns of linkage disequilibrium and genetic divergence in an old inversion polymorphism in Drosophila melanogaster (In(3R)Payne) known to be associated with climate change adaptation and a recent invasion event into Australia. We extracted, karyotyped and sequenced whole chromosomes from two Australian populations, so that changes in the arrangement of the alleles between geographically separated tropical and temperate areas could be compared. Chromosome-wide linkage disequilibrium (LD) analysis revealed strong LD within the region spanned by In(3R)Payne. This genomic region also showed strong differentiation between the tropical and the temperate populations, but no differentiation between different karyotypes from the same population, after controlling for chromosomal arrangement. Patterns of differenti...Continue Reading

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Citations

Jan 23, 2016·Molecular Biology and Evolution·Martin KapunThomas Flatt
Dec 22, 2015·Molecular Ecology·Alexandra WeyrichJörns Fickel
Mar 18, 2016·Genome Biology and Evolution·Marte SodelandHalvor Knutsen
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Jun 16, 2018·Journal of Evolutionary Biology·Esra DurmazThomas Flatt
Dec 4, 2019·Pest Management Science·Jian PuHenry Chung
Feb 14, 2019·Disasters·Elena Fiddian-Qasmiyeh
May 22, 2020·Genome Biology and Evolution·Jakob McBroomeRussell Corbett-Detig
Jul 12, 2017·Ecology and Evolution·Stefan Caddy-RetalicAndrew J Lowe
Jul 11, 2018·Proceedings of the National Academy of Sciences of the United States of America·Changde ChengNora J Besansky
Aug 29, 2018·Genetica·Maria GalludoFrancesc Mestres
Mar 24, 2021·Biological Reviews of the Cambridge Philosophical Society·Yiwen WangBernard Moussian

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