Genomic evidence for the Old divergence of Southern European wolf populations

Proceedings. Biological Sciences
Pedro SilvaRaquel Godinho

Abstract

The grey wolf (Canis lupus) is one of the most widely distributed mammals in which a variety of distinct populations have been described. However, given their currently fragmented distribution and recent history of human-induced population decline, little is known about the events that led to their differentiation. Based on the analysis of whole canid genomes, we examined the divergence times between Southern European wolf populations and their ancient demographic history. We found that all present-day Eurasian wolves share a common ancestor ca 36 000 years ago, supporting the hypothesis that all extant wolves derive from a single population that subsequently expanded after the Last Glacial Maximum. We also estimated that the currently isolated European populations of the Iberian Peninsula, Italy and the Dinarics-Balkans diverged very closely in time, ca 10 500 years ago, and maintained negligible gene flow ever since. This indicates that the current genetic and morphological distinctiveness of Iberian and Italian wolves can be attributed to their isolation dating back to the end of the Pleistocene, predating the recent human-induced extinction of wolves in Central Europe by several millennia.

References

Jun 1, 1997·Computer Applications in the Biosciences : CABIOS·A Rambaut, N C Grassly
Jan 17, 2002·Proceedings of the National Academy of Sciences of the United States of America·Sudhir Kumar, Sankar Subramanian
Jul 13, 2004·Molecular Ecology·Eli GeffenRobert K Wayne
Oct 2, 2004·Science·Anthony D BarnoskyAlan B Shabel
Dec 13, 2005·Nature·Kerstin Lindblad-TohEric S Lander
Nov 17, 2006·Molecular Ecology·Malgorzata PilotStephan M Funk
Jun 23, 2007·Current Biology : CB·Jennifer A LeonardBlaire Van Valkenburgh
Aug 11, 2007·Molecular Ecology·L E CarmichaelC Strobeck
Sep 20, 2007·Molecular Ecology·Bridgett M VonholdtRobert K Wayne
Feb 5, 2009·Genetics·Melissa M GrayRobert K Wayne
Dec 8, 2009·Genetics·Aaron K WongMark W Neff
Apr 23, 2010·BMC Evolutionary Biology·Małgorzata PilotElena Tsingarska
Dec 24, 2010·Molecular Biology and Evolution·Pontus SkoglundMattias Jakobsson
May 3, 2011·Trends in Ecology & Evolution·Mark de BruynMichael Hofreiter
Jan 1, 2014·GigaScience·Oscar C Bedoya-ReinaWebb Miller
Jan 11, 2014·Science·William J RippleAaron J Wirsing
Jan 24, 2014·PLoS Genetics·Adam H FreedmanJohn Novembre
Dec 20, 2014·Science·Guillaume ChapronLuigi Boitani
Dec 17, 2015·Cell Research·Guo-Dong WangYa-Ping Zhang
Dec 19, 2015·Genome Research·Zhenxin FanRobert K Wayne
Jun 4, 2016·Science·Laurent A F FrantzGreger Larson
Feb 15, 2017·Scientific Reports·C PachecoR Godinho
May 3, 2018·Systematic Biology·Andrew RambautMarc A Suchard
Aug 3, 2018·Proceedings. Biological Sciences·Christophe DufresnesLuca Fumagalli
Aug 4, 2018·Molecular Ecology·Daniel Gómez-SánchezOscar Ramírez
Sep 22, 2018·Scientific Reports·Pedro SilvaRaquel Godinho
Oct 23, 2018·Current Biology : CB·Shyam GopalakrishnanM Thomas P Gilbert
Jul 13, 2019·Molecular Biology and Evolution·Evan KochJohn Novembre

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Datasets Mentioned

BETA
SRP062184
SRP044399

Methods Mentioned

BETA
genotyping

Software Mentioned

Galaxy
Tracer
IT
ancCR
Admixture
ms
Seq
ancIT
gen
Variant Call Format ( VCF

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