Genomic evidence that resource-based trade-offs limit host-range expansion in a seed beetle

Evolution; International Journal of Organic Evolution
Zachariah Gompert, Frank J Messina


Trade-offs have often been invoked to explain the evolution of ecological specialization. Phytophagous insects have been especially well studied, but there has been little evidence that resource-based trade-offs contribute to the evolution of host specialization in this group. Here, we combine experimental evolution and partial genome resequencing of replicate seed beetle selection lines to test the trade-off hypothesis and measure the repeatability of evolution. Bayesian estimates of selection coefficients suggest that rapid adaptation to a poor host (lentil) was mediated by standing genetic variation at multiple genetic loci and involved many of the same variants in replicate lines. Sublines that were then switched back to the ancestral host (mung bean) showed a more gradual and variable (less repeatable) loss of adaptation to lentil. We were able to obtain estimates of variance effective population sizes from genome-wide differences in allele frequencies within and between lines. These estimates were relatively large, which suggests that the contribution of genetic drift to the loss of adaptation following reversion was small. Instead, we find that some alleles that were favored on lentil were selected against during reversi...Continue Reading

Associated Datasets


May 25, 2002·Nature·Patrik NosilCristina P Sandoval
Oct 2, 2002·Evolution; International Journal of Organic Evolution·P Nosil
Jan 23, 2003·Proceedings of the National Academy of Sciences of the United States of America·Tim F CooperRichard E Lenski
May 31, 2003·Nature Reviews. Genetics·Santiago F Elena, Richard E Lenski
Jul 1, 2004·Nature Genetics·Mark A Gillespie, Michael A Rudnicki
Feb 9, 2005·Evolution; International Journal of Organic Evolution·Frank J Messina
Jun 2, 2005·Evolution; International Journal of Organic Evolution·Patrik NosilDaniel J Funk
Aug 28, 2007·Genetics·Per Erik Jorde, Nils Ryman
Jun 6, 2008·Proceedings of the National Academy of Sciences of the United States of America·Zachary D BlountRichard E Lenski
Jul 18, 2008·Epidemiology·John P A Ioannidis
Aug 19, 2008·The American Naturalist·Sara Via
Aug 30, 2008·Science·Rowan D H BarrettDolph Schluter
Dec 24, 2008·PloS One·Roosa Leimu, Markus Fischer
Jan 13, 2009·Nature Genetics·Henrique TeotónioAnthony D Long
Mar 11, 2009·The American Naturalist·Joe Hereford
May 20, 2009·Bioinformatics·Heng Li, Richard Durbin
Feb 25, 2010·Current Biology : CB·Jonathan K PritchardGraham Coop
May 22, 2010·Trends in Ecology & Evolution·Katalin CsilléryOlivier François
Jul 9, 2010·Proceedings. Biological Sciences·James A Fordyce
Aug 17, 2010·Bioinformatics·Robert C Edgar
Sep 17, 2010·Nature·Molly K BurkeAnthony D Long
Feb 19, 2011·Annual Review of Marine Science·Eric Sanford, Morgan W Kelly
Dec 3, 2011·Evolution; International Journal of Organic Evolution·Alison B DuncanOliver Kaltz
Mar 13, 2012·Molecular Ecology·Thomas L ParchmanC Alex Buerkle
Apr 7, 2012·Nature·Felicity C JonesDavid M Kingsley
Apr 12, 2012·PloS One·Sergio Castrezana, Jeremy M Bono
Jul 5, 2012·Evolution; International Journal of Organic Evolution·Zachariah GompertC Alex Buerkle
Oct 26, 2012·Proceedings. Biological Sciences·Susanna Remold
Oct 10, 2013·Evolution; International Journal of Organic Evolution·Jill T AndersonThomas Mitchell-Olds
Dec 21, 2013·Ecology Letters·Zachariah GompertPatrik Nosil
May 17, 2014·Science·Víctor Soria-CarrascoPatrik Nosil
Aug 6, 2014·Proceedings of the National Academy of Sciences of the United States of America·Alejandra Rodríguez-VerdugoAlbert F Bennett

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Oct 28, 2016·Molecular Ecology·Zachariah GompertPatrik Nosil
Feb 22, 2017·Annals of the New York Academy of Sciences·Kim L Vertacnik, Catherine R Linnen
Apr 5, 2018·Molecular Ecology·Samridhi ChaturvediZachariah Gompert
Aug 11, 2018·Evolution; International Journal of Organic Evolution·Mrudula SaneDeepa Agashe
May 14, 2019·Journal of Economic Entomology·Frank J MessinaZachariah Gompert
Jan 1, 2020·Evolution; International Journal of Organic Evolution·Micah G FreedmanSharon Y Strauss
Apr 10, 2019·Molecular Ecology·Alexandre RêgoZachariah Gompert
Nov 29, 2020·Science Advances·M L ForisterZ Gompert
Dec 2, 2020·Nature Ecology & Evolution·Isabel S MagalhaesAndrew D C MacColl
Apr 3, 2020·Current Opinion in Insect Science·Heinz Müller-SchärerYan Sun
Jun 13, 2021·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Frank J MessinaZachariah Gompert

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