Genomic landscape of intracranial meningiomas

Journal of Neurosurgery
Wenya Linda BiIan F Dunn

Abstract

Meningiomas are the most common primary intracranial neoplasms in adults. Current histopathological grading schemes do not consistently predict their natural history. Classic cytogenetic studies have disclosed a progressive course of chromosomal aberrations, especially in high-grade meningiomas. Furthermore, the recent application of unbiased next-generation sequencing approaches has implicated several novel genes whose mutations underlie a substantial percentage of meningiomas. These insights may serve to craft a molecular taxonomy for meningiomas and highlight putative therapeutic targets in a new era of rational biology-informed precision medicine.

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Citations

Jul 28, 2016·Frontiers in Surgery·Wenya Linda BiIan F Dunn
Mar 26, 2016·Neurosurgery Clinics of North America·Wenya Linda BiIan F Dunn
Jul 15, 2017·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Nives Pećina-ŠlausReno Hrašćan
Jul 20, 2016·Cancers·Nives Pećina-ŠlausMirna Lechpammer
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Jun 2, 2018·Neurosurgical Focus·Michael KarsyD Ryan Ormond
Nov 20, 2016·Surgical Neurology International·Paolo MissoriVincenzo Esposito
Apr 3, 2018·Neurosurgical Focus·Wenya Linda BiIan F Dunn
May 30, 2017·PloS One·Yu MeiIan F Dunn
Jun 12, 2019·Neurosurgical Review·Jean-Michel LeméeTorstein R Meling
May 18, 2018·F1000Research·Nawal ShaikhJeffrey Raizer
Jan 24, 2020·Frontiers in Oncology·May Al-RashedMalak Abedalthagafi
Jul 18, 2017·NPJ Genomic Medicine·Wenya Linda BiRameen Beroukhim
Jan 16, 2021·International Journal of Molecular Sciences·Suha BachirSoma Sengupta
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Jun 17, 2021·Operative Neurosurgery·Antonio Aversa, Ossama Al-Mefty
Jun 1, 2021·Neuropathology and Applied Neurobiology·Julien BoettoFranck Bielle
Jun 25, 2021·Neurosurgery·Wenya Linda Bi, Sandro Santagata
Jun 4, 2020·Neuroendocrinology·Thomas GraillonMichael Buchfelder
Dec 7, 2021·Frontiers in Oncology·María González-TablasMaría Dolores Tabernero

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