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Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions

bioRxiv

Jun 3, 2018

Idan NurickRan Elkon

Abstract

Background. Our appreciation of the critical role of the 3D organization of the genome in gene regulation is steadily increasing. Recent 3C-based deep sequencing techniques elucidated a hierarchy of structures that underlie the spatial organization of the genome in the nucleus. At the t...read more

Mentioned in this Paper

Meta-Analysis (Publications)
Nucleic Acid Sequence Based Analysis
Meta Analysis (Statistical Procedure)
Invariant Natural Killer T-Cells
Genome
Three-dimensional
Regulation of Biological Process
Transcription, Genetic
Tissue-Specific Gene Expression
Promoter
8
Paper Details
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Genomic meta-analysis of the interplay between 3D chromatin organization and gene expression programs under basal and stress conditions

bioRxiv

Jun 3, 2018

Idan NurickRan Elkon

PMID: 990337766

DOI: 10.1101/337766

Abstract

Background. Our appreciation of the critical role of the 3D organization of the genome in gene regulation is steadily increasing. Recent 3C-based deep sequencing techniques elucidated a hierarchy of structures that underlie the spatial organization of the genome in the nucleus. At the t...read more

Mentioned in this Paper

Meta-Analysis (Publications)
Nucleic Acid Sequence Based Analysis
Meta Analysis (Statistical Procedure)
Invariant Natural Killer T-Cells
Genome
Three-dimensional
Regulation of Biological Process
Transcription, Genetic
Tissue-Specific Gene Expression
Promoter
8

Similar Papers Found In These Feeds

Nuclear Architecture (Keystone)

The 3-D organization of chromatin is an important factor in the regulation of gene expression. Find the latest research on nuclear architecture in this feed.

CREs: Gene & Cell Therapy

Gene and cell therapy advances have shown promising outcomes for several diseases. The role of cis-regulatory elements (CREs) is crucial in the design of gene therapy vectors. Here is the latest research on CREs in gene and cell therapy.

Related Papers

Current Opinion in Cell Biology

Genome organization at different scales: nature, formation and function

Current Opinion in Cell BiologyApril 10, 2018
Jacques Serizay, Julie Ahringer
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