PMID: 8592076Jan 1, 1996Paper

Genomic organization and sequence of D12S53E (Pmel 17), the human homologue of the mouse silver (si) locus

The Journal of Investigative Dermatology
T BailinR A Spritz

Abstract

We have determined the DNA sequence and genomic organization of D12S53E (Pmel 17), the human homologue of the mouse silver (si) locus. D12S53E encodes a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. D12S53E is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.

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Citations

Sep 11, 2004·Pigment Cell Research·Lawrence S StennettI Caroline Le Poole
Sep 16, 2005·Pigment Cell Research·Alexander C TheosMichael S Marks
Jan 13, 2006·Proceedings of the National Academy of Sciences of the United States of America·Leigh Anne ClarkKeith E Murphy
Sep 24, 2015·Biopolymers·Nikolaos N Louros, Vassiliki A Iconomidou
Feb 17, 2007·The Journal of Biological Chemistry·Julio C ValenciaVincent J Hearing
Jan 30, 2007·Animal Genetics·M ReissmannG A Brockmann
Nov 25, 2003·The Journal of Investigative Dermatology·Sarah E NicholsMichael S Marks

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