PMID: 8584230Oct 13, 1995Paper

Genomic structure and tissue distribution of the mouse dopamine D4 receptor

Neuroscience Letters
T SuzukiT Nagatsu

Abstract

The mouse dopamine D4 receptor gene was isolated from a genomic DNA library by plaque hybridization. The D4 receptor gene encoded an open reading frame consisting of 387 amino acids, interrupted by three introns. Distribution of the D4 receptor mRNA in brain regions and peripheral tissues of mice was examined by reverse transcription-polymerase chain reaction (RT-PCR). There was a remarkable expression of the receptor mRNA in various brain regions, showing the highest expression level in the cerebellum. Also, in the peripheral tissues a high level expression of the D4 mRNA was detected in the eye, adrenal gland and testes. We observed several differences in tissue distribution of the D4 mRNA in mice from that reported in other mammalian species.

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Citations

Nov 20, 2003·Neuroscience and Biobehavioral Reviews·Davide ViggianoAdolfo G Sadile
Oct 18, 2000·European Journal of Pharmacology·J N OakH H Van Tol
Jul 31, 1998·Progress in Neuro-psychopharmacology & Biological Psychiatry·F I TaraziR J Baldessarini
Nov 19, 1997·Neuroscience Letters·J Mulcrone, R W Kerwin
Sep 1, 1997·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·F I TaraziJ L Neumeyer
Sep 28, 1998·The European Journal of Neuroscience·C MaugerF Monsma
Feb 24, 2001·Fundamental & Clinical Pharmacology·S K Kulkarni, I Ninan
Jan 19, 2016·Frontiers in Neuroanatomy·Juan Pérez-FernándezManuel A Pombal
Jul 29, 2015·Neuroscience and Biobehavioral Reviews·Haritz Jiménez-UrbietaMaría C Rodriguez-Oroz
Sep 10, 2008·Experimental Eye Research·Laura L KlittenMorten Møller
May 15, 2015·Journal of Neural Transmission·Nasim VousooghiMohammad Reza Zarrindast
Jun 30, 2000·Japanese Journal of Pharmacology·D M Helmeste, S W Tang
Sep 24, 2008·Handbook of Clinical Neurology·Richard B Mailman, Xuemei Huang
Mar 17, 2007·The Journal of Comparative Neurology·Belén GagoAlicia Rivera
Jul 4, 2018·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Nasim VousooghiMohammad Reza Zarrindast
Nov 4, 2004·Journal of Receptor and Signal Transduction Research·Frank I TaraziRoss J Baldessarini

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