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Genomics via Optical Mapping (I): 0-1 Laws for Mapping with Single Molecules

bioRxiv

Nov 22, 2013

Thomas S Anantharaman, Bud (Bhubaneswar) Mishra

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Abstract

The genomic data that can be collected from a single DNA molecule by the best chemical and optical methods (e.g., using technologies from OpGen, BioNanoGenomics, NABSys, PacBio, etc.) are badly corrupted by many poorly understood noise processes. Thus, single molecule technology derives...read more

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Optical Methods
Genome
Molecular Assembly/Self Assembly
Optical Restriction Mapping
Bounded by
DNA
Analysis
Computed (Procedure)
Genomics
Paper Details
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Genomics via Optical Mapping (I): 0-1 Laws for Mapping with Single Molecules

bioRxiv

Nov 22, 2013

Thomas S Anantharaman, Bud (Bhubaneswar) Mishra

DOI: 10.1101/000844

Abstract

The genomic data that can be collected from a single DNA molecule by the best chemical and optical methods (e.g., using technologies from OpGen, BioNanoGenomics, NABSys, PacBio, etc.) are badly corrupted by many poorly understood noise processes. Thus, single molecule technology derives...read more

Mentioned in this Paper

Optical Methods
Genome
Molecular Assembly/Self Assembly
Optical Restriction Mapping
Bounded by
Paper Details
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