Genotoxic effect of copper on salivary gland polytene chromosomes of Chironomus riparius Meigen 1804 (Diptera, Chironomidae)

Environmental Pollution
Paraskeva MichailovaGabriella Sella

Abstract

The genotoxic action of copper (Cu) on the polytene chromosomes of Chironomus riparius was investigated by analysing structural and functional chromosome aberrations of fourth instars larvae hatched from eggs subject to acute (48 h) exposure with three environmentally relevant concentrations of aqueous Cu (0.005, 0.01, 0.05 mg/l). A dose dependent relationship was observed between Cu concentration and frequency of chromosomal aberrations. A significantly higher frequency of functional alterations, specifically decondensed centromeres and telomeres, and reduction in activity of Balbiani rings, was observed in treated material compared to control. A comparison of breakpoints resulting from treatment with chromium and lead from earlier studies with those Cu-induced identified a series of chromosomal weak points particularly vulnerable to trace metals. We also show that the appearance of structural and functional chromosome aberrations are more sensitive indicators of acute Cu toxicity in chironomid larvae than changes in external morphology.

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Citations

Sep 9, 2011·Molecular Genetics and Genomics : MGG·Giampaolo ZampicininiGabriella Sella
Jan 27, 2012·Aquatic Toxicology·José-Luis Martínez-GuitarteGloria Morcillo
Oct 23, 2010·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Mónica MoralesGloria Morcillo
Dec 16, 2006·The Science of the Total Environment·R PlanellóG Morcillo
Mar 10, 2015·Bulletin of Environmental Contamination and Toxicology·Hélène ArambourouJean-Nicolas Beisel
Mar 17, 2019·Insects·Peter H Adler, Gregory W Courtney

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