PMID: 9544197Apr 17, 1998Paper

Genotoxic effects of heavy metals: comparative investigation with plant bioassays

Environmental and Molecular Mutagenesis
H SteinkellnerSiegfried Knasmüller

Abstract

The potential use of micronucleus assays in plants for the detection of genotoxic effects of heavy-metal ions was investigated. Three different plant systems were comparatively investigated in micronucleus tests with Tradescantia pollen mother cells (Trad MCN) and micronucleus tests with meristematic root tip cells of Allium cepa and Vicia faba (Allium/ Vicia MCN). As3+, Pb2+, Cd2+, Zn2+ caused a dose-dependent increase of MCN frequencies in all three test systems. Cu2+ gave consistently negative responses in all three tests; Zn2+ caused only a moderate, statistically not significant increase of MCN frequencies in Vicia. The ranking of genotoxic potencies in all three tests was in the descending order: As3+ > Pb2+ > Cd2+ > Zn2+ Cu2+. In experiments with Tradescantia, induction of MCN was observed in a concentration range between 1 and 10 mM, whereas in tests with root tip cells, higher concentrations (10-1,000 mM) were required to show significant effects. Further increase of the exposure levels caused toxic effects (reduction of root growth), cell division delays, and a decrease of MCN frequencies. Comparisons by linear regression analyses indicated that the sensitivity of the three bioassays for heavy metals decreases in the ...Continue Reading

Citations

Oct 5, 2010·Analytical and Bioanalytical Chemistry·Ana Lilia Barrán-BerdónFrancisca Fernández-Piñas
Oct 29, 2013·Environmental Monitoring and Assessment·Elisângela DüsmanTiciane Pokrywiecki Sauer
Nov 21, 2008·Biological Trace Element Research·Flávia de Castro PereiraElisângela de Paula Silveira-Lacerda
Jul 4, 2001·Trends in Plant Science·I KovalchukB Hohn
May 24, 2003·Applied Microbiology and Biotechnology·O V SinghR K Jain
Nov 17, 2009·Ecotoxicology and Environmental Safety·J S BarbosaS R Batistuzzo de Medeiros
Sep 5, 2009·Chemosphere·Claire-Emmanuelle Marcato-RomainEric Pinelli
Dec 2, 2008·Mutation Research·M S MonteiroC Santos
Dec 9, 2015·Ecotoxicology and Environmental Safety·Maria Nilza Corrêa MartinsTatiana da Silva Souza
Apr 24, 2008·Mutation Research·Tomás GichnerJirina Száková
Jun 19, 2007·The Science of the Total Environment·Huilan YiLin Jiang
Aug 11, 2007·Mutation Research·Eric BéraudJean-François Férard
Oct 15, 2005·Ecotoxicology and Environmental Safety·Tomás GichnerKaterina Demnerová
Jun 28, 2005·Ecotoxicology and Environmental Safety·V V Arkhipchuk, N N Garanko
Mar 19, 2002·Environmental Research·Silvano MonarcaGiuseppe Nardi
Sep 17, 2011·Mutation Research·Bertrand PourrutEric Pinelli
Jul 8, 2014·The Science of the Total Environment·Miroslav MišíkSiegfried Knasmueller

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