PMID: 9434847Jan 22, 1998Paper

Genotoxicity assessment of suspended particulate matter in the Elbe river: comparison of Salmonella microsome test, arabinose resistance test, and umu-test

Mutation Research
H H VahlJ Westendorf

Abstract

This study evaluates the applicability of three bacterial short-term genotoxicity test systems to aquatic suspended particulate matter of the Elbe river. This material was sampled in sedimentation vessels after deposition periods of one month. It was extracted in a Soxhlet apparatus with toluene and methanol. Aqueous elutriates were prepared additionally. A solid phase method was developed that enables to incubate bacteria in contact with the particulate material. The test battery consists of two mutagenicity assays (the Ames-test and the Ara-test) and an SOS induction assay (the umu-test). Both mutagenicity assays came to nearly the same assessment of the samples of particulate matter of the Elbe. The quantitative response, however, was higher in the Ara-test. The particulate river material generally induced lower genotoxic potencies in the umu-test than in the mutagenicity assays. This lead to a completely different outcome of the umu-test; 29 out of 35 mutagenic samples were not SOS inducing. No quantitative or rank correlations between the concentrations of anthropogenic contaminants (PAHs, chlorinated hydrocarbons and metals) and the observed effects could be established on a 90% confidence limit. However, there is obvious...Continue Reading

References

Apr 1, 1977·Mutation Research·T YahagiT Sugimura
Feb 1, 1976·Mutation Research·M H Green, W J Muriel
Jan 1, 1988·Mutation Research·M D Shelby
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Citations

Dec 21, 2007·Environmental Monitoring and Assessment·Mehtap KutluKiymet Güven
May 16, 2009·Environmental Monitoring and Assessment·Ozlem Cakal ArslanHale Guner
Aug 26, 2009·Environmental Science and Pollution Research International·Markus Hecker, Henner Hollert
Sep 10, 2013·Ecotoxicology and Environmental Safety·B Huerta BuitragoS Waara
Jul 18, 2003·Chemosphere·Lei ShenHeinrich Huehnerfuss
Jun 6, 2000·Mutation Research·U KammannH Steinhart
Sep 15, 2012·BMC Complementary and Alternative Medicine·Fadwa ChaabaneLeila Chekir-Ghedira
Nov 15, 2011·Mutation Research·Françoise Vincent-HubertJacek Tronczynski
Oct 12, 2010·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Maja ŠrutGöran I V Klobučar
Jun 24, 2008·Mutation Research·P David JosephyFilomena Ng
Dec 2, 2004·Mutation Research·Takeshi OheKeiji Wakabayashi
Dec 2, 2004·Mutation Research·Guosheng Chen, Paul A White
Jul 23, 2004·Environmental Toxicology·Janina BarsieneOdd Ketil Andersen
May 10, 2005·Environmental and Molecular Mutagenesis·Georg ReifferscheidClaudia Schmid
Oct 12, 2004·Environmental and Molecular Mutagenesis·Katsuaki YasunagaKunie Yoshikawa
Jul 27, 2010·Chemistry & Biodiversity·Mohamed Ben SghaierKamel Ghedira
Mar 2, 2012·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Simone GallubaJörg Oehlmann
Dec 15, 2015·Beilstein Journal of Nanotechnology·Richard L Marchese RobinsonRobert Rallo
Dec 10, 2016·Ecotoxicology·Françoise Vincent-HubertCatherine Gourlay-France

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