PMID: 2114542Jul 1, 1990Paper

Genotoxicity of ethyl carbamate in the Drosophila wing spot test: dependence on genotype-controlled metabolic capacity

Mutation Research
A Frölich, F E Würgler

Abstract

Ethylcarbamate has a clear genotoxic potential in Drosophila melanogaster. In the somatic mutation and recombination test (SMART) it induces, in a dose-dependent manner, single spots as well as twin spots. The twin spots indicate a recombinogenic activity of ethyl carbamate. A strong strain difference demonstrates that the metabolic activation of ethyl carbamate to DNA binding metabolites most probably also in Drosophila involves cytochrome P450-dependent enzyme activities.

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Citations

Dec 1, 1992·Mutation Research·E W Vogel
May 1, 1994·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·U GrafE Díaz Carrillo
Jan 1, 1996·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S K Abraham, U Graf
Apr 21, 2001·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J R LazutkaV Dedonyte
Nov 28, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R El HamssA Muñoz Serrano
Dec 29, 1999·Mutation Research·R el HamssM Idaomar
Sep 30, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·María Eugenia Heres-PulidoAngel Durán-Díaz
Oct 4, 2007·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Edson José FragiorgeMário Antônio Spanó
Jun 7, 2008·Environmental and Molecular Mutagenesis·Vânia Maria Sartini Dutra PimentaLuiz Alfredo Pavanin
Apr 21, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·P LaohavechvanichA J Ketterman
Dec 27, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Luis Felipe Santos-CruzMaría Eugenia Heres-Pulido
Jan 1, 1996·Environmental and Molecular Mutagenesis·C SanerC Sengstag
Dec 22, 2004·Environmental and Molecular Mutagenesis·Vânia Maria Sartini Dutra Pimenta, Júlio César Nepomuceno
Dec 31, 2020·Journal of Toxicology and Environmental Health. Part a·Orawan KhantamatPiya Temviriyanukul
May 26, 2021·International Journal of Biological Macromolecules·Maria Paula Carvalho NavesMário Antônio Spanó
Mar 1, 2020·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Victor Constante OliveiraMário Antônio Spanó

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