PMID: 2507911Oct 1, 1989Paper

Genotoxicity of ziram established through wing, eye and female germ-line mosaic assays and the sex-linked recessive lethal test in Drosophila melanogaster

Mutation Research
N K TripathyC C Das

Abstract

The genotoxicity of ziram (zinc-dimethyl dithiocarbamate, CAS No. 137-30-4), a carbamate fungicide, is studied in the wing, eye and female germ-line mosaic assays and the sex-linked recessive lethal test in Drosophila melanogaster. First-, second- and third-instar larvae, carrying suitable recessive genetic markers on their first and third chromosomes, were exposed to ziram. Wings and eyes of adults were screened for the induction of mosaic spots and the eggs laid by adult females for germ-line mosaicism. The Basc method was used to detect sex-linked recessive lethals. Ziram is genotoxic to the somatic and germ cells of Drosophila melanogaster.

References

Aug 1, 1979·Environmental Health Perspectives·C Ramel, J Magnusson
Jan 1, 1976·Developmental Biology·A Garcia-BellidoG Morata
Jan 1, 1974·Molecular & General Genetics : MGG·A Garcia-Bellido, J Dapena
May 15, 1973·Experientia·J P Seiler
May 1, 1970·Mutation Research·M A Kastenbaum, K O Bowman
Jan 1, 1984·Environmental Mutagenesis·U GrafP G Kale

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Citations

Jan 1, 1994·Teratogenesis, Carcinogenesis, and Mutagenesis·P MosessoF Palitti
Sep 16, 1998·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J TinklerJ Bootman
Jul 1, 2006·Critical Reviews in Toxicology·Douglas McGregor

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