Genotoxicity, oxidative stress, and biochemical biomarkers of exposure to green synthesized cadmium nanoparticles in Oreochromis niloticus (L.).

Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP
Ahmed Th A IbrahimAntoni Sureda

Abstract

The considerable increment in the use of Nanoparticles in the industry has been recognized as an environmental concern today. Therefore, this study aimed to investigate the toxicity effects of green synthesized cadmium nanoparticles [Cd]NPs using Moringa oleifera leaves extract on multi-biomarkers in Oreochromis niloticus after four weeks of exposure. The results showed that LC50 values of [Cd]NPs for 24, 48, 72 and 96 h were 2.17, 1.75, 1.49 and 1.22 mg l-1, respectively. There was a significant decrease in the number of white and red blood cells, hemoglobin, hematocrit, mean corpuscular hemoglobin concentration value in fish exposed to [Cd]NPs. The mean corpuscular volume and neutrophils were increased. [Cd]NPs exposure to fish has led to cytotoxic and genotoxic changes in the erythrocytes. Significant changes were observed in the cortisol, triiodothyronine, and thyroxine levels of the fish exposed to [Cd]NPs. The activities of aspartate aminotransferase and alanine aminotransferase increased. Glucose, total lipids, urea, and creatinine levels increased in the serum of fish exposed to [Cd]NPs, whereas total protein contents and alkaline phosphatase activity decreased. A significant reduction was observed in glycogen, total an...Continue Reading

References

Jan 1, 1978·Methods in Enzymology·J A Buege, S D Aust
Jan 1, 1990·Methods in Enzymology·R L LevineE R Stadtman
Jan 1, 1984·Methods in Enzymology·H Aebi
Jul 27, 2001·Environmental and Molecular Mutagenesis·L Serrano-García, R Montero-Montoya
Feb 4, 2006·Science·Andre NelNing Li
Oct 13, 2006·Archives of Environmental Contamination and Toxicology·H M Lizardo-DaudtChristopher J Kennedy
Nov 23, 2007·The Science of the Total Environment·Sabine A BlaserKonrad Hungerbühler
Jul 26, 2008·Nature Nanotechnology·Renata Behra, Harald Krug
Nov 7, 2008·Analytical and Bioanalytical Chemistry·Marinella FarréDamià Barceló
Feb 26, 2010·Particle and Fibre Toxicology·Xifei YangZhixiong Zhuang
Apr 9, 2011·Environment International·Benjamin J Shaw, Richard D Handy
May 16, 2012·Chemosphere·Cleoni dos Santos CarvalhoMarisa Narciso Fernandes
Nov 28, 2012·Bulletin of Environmental Contamination and Toxicology·S Garcia-SantosJ M Wilson
Jan 15, 2013·Marine Pollution Bulletin·Janina BaršienėAleksandras Michailovas
Jan 1, 2012·Journal of Environmental Sciences (China)·Rajakumar Govindasamy, Abdul Abdul Rahuman
Aug 2, 2013·Scientific Reports·Chang PanJin-Peng Sun
Nov 12, 2013·Food Chemistry·Estelamar Maria Borges TeixeiraLucas Arantes-Pereira
Mar 22, 2014·Chemical Society Reviews·Yi ZhangBing Yan
Apr 19, 2015·Ecotoxicology and Environmental Safety·Rajinder Jindal, Sakshi Verma
Feb 28, 2016·Aquatic Toxicology·Minjie ChenHailin Wang
Jan 25, 2017·The Science of the Total Environment·Roberto Carlos Valerio-GarcíaFernando Martínez-Jerónimo
Jul 21, 2016·Toxicology Research·Yan ZhangShang Gao
Apr 11, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Ahmed Th A IbrahimAlaa G M Osman

❮ Previous
Next ❯

Citations

Feb 28, 2021·Environmental Science and Pollution Research International·Amr Adel Abdel-KhalekWafaa S F Hasheesh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.