Genotypic diversity in Oenococcus oeni by high-density microarray comparative genome hybridization and whole genome sequencing

Applied Microbiology and Biotechnology
Anthony R BornemanPaul J Chambers

Abstract

Many bacteria display substantial intra-specific genomic diversity that produces significant phenotypic variation between strains of the same species. Understanding the genetic basis of these strain-specific phenotypes is especially important for industrial microorganisms where these characters match individual strains to specific industrial processes. Oenococcus oeni, a bacterium used during winemaking, is one such industrial species where large numbers of strains show significant differences in commercially important industrial phenotypes. To ascertain the basis of these phenotypic differences, the genomic content of ten wine strains of O. oeni were mapped by array-based comparative genome hybridization (aCGH). These strains comprised a genomically diverse group in which large sections of the reference genome were often absent from individual strains. To place the aCGH results in context, whole genome sequence was obtained for one of these strains and compared with two previously sequenced, unrelated strains. While the three strains shared a core group of conserved ORFs, up to 10% of the coding potential of any one strain was specific to that isolate. The genome of O. oeni is therefore likely to be much larger than that prese...Continue Reading

Associated Datasets

May 24, 2010·Anthony R BornemanAnthony R Borneman

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Citations

Aug 27, 2011·Applied Microbiology and Biotechnology·Eveline J Bartowsky, Anthony R Borneman
Aug 9, 2011·Journal of Industrial Microbiology & Biotechnology·Melissa L Ivey, Trevor G Phister
Jun 6, 2014·PloS One·Maria DimopoulouMarguerite Dols-Lafargue
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Nov 29, 2011·International Journal of Food Microbiology·Maria DimopoulouMarguerite Dols-Lafargue
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Apr 28, 2016·BMC Genomics·Peter R Sternes, Anthony R Borneman
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Jun 28, 2018·Frontiers in Microbiology·Maria DimopoulouMarguerite Dols-Lafargue
Oct 7, 2021·Microbiology Spectrum·Cristobal A OnettoSimon A Schmidt

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