Genotypic variability and antifungal susceptibility of Candida tropicalis isolated from patients with candiduria

Revista iberoamericana de micología
Adriana Araújo de AlmeidaKelly Mari Pires de Oliveira

Abstract

Candida tropicalis is an emerging major human pathogen in nosocomial infections, and it is considered the second or third species of Candida most isolated from urine cultures. The study aimed at characterizing genotypically C. tropicalis strains from patients with candiduria in a university hospital, and assessed the antifungal susceptibility profile. The study was conducted with hospitalized patients who developed urinary tract infection from C. tropicalis from June 2010 to June 2011 at the Grande Dourados University Hospital of the Federal University, Dourados, MS, Brazil. Susceptibility to the antifungal agents amphotericin B and fluconazole was determined by broth microdilution. The genotypic variability of isolates of C. tropicalis was analyzed by microsatellite markers and RAPD-PCR. Only one isolate was resistant to amphotericin B (MIC→16μg/ml); the others were susceptible to fluconazole and amphotericin B. The genotypic variability by RAPD-PCR resulted in distinct profiles for RAPD markers. A total of 10 alleles were observed for the microsatellite loci, URA3 and CT14, which were grouped differently, and four associations were observed for locus URA3 and eight for locus CT14. C. tropicalis isolates from urine were suscep...Continue Reading

References

Feb 7, 2001·Clinical Microbiology Reviews·D R Soll
Oct 15, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Y L LiT C Chang
Mar 19, 2004·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A M TortoranoUNKNOWN ECMM Working Group on Candidaemia
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Hilmar WisplinghoffMichael B Edmond
Aug 21, 2007·The Journal of Infection·Navin PaulDilip Mathai
Mar 28, 2008·Revista Da Sociedade Brasileira De Medicina Tropical·Bruno Aragão RochaThelma Suely Okay
Apr 9, 2008·Emerging Infectious Diseases·Marie Desnos-OllivierUNKNOWN Yeasts Group
Apr 9, 2010·Clinical Microbiology Reviews·Jacqueline M Achkar, Bettina C Fries
Apr 24, 2010·Journal of Medical Microbiology·Rajendra J KothavadeM H Panthaki
Aug 28, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Matthew E FalagasKonstantinos Z Vardakas
Apr 29, 2011·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hung-Wei ChiJung-Chung Lin
Sep 17, 2011·Internal Medicine·Thibaut FraisseAlbert Sotto
Sep 22, 2011·Indian Journal of Pathology & Microbiology·Manisha JainAradhana Bhargava
Oct 13, 2011·Medical Mycology·Betil Ozhak-BaysanFiliz Gunseren
Dec 7, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James L WynnUNKNOWN NICHD Neonatal Research Network
Jan 31, 2012·Revista iberoamericana de micología·Ana Caroline Akeme YamamotoRosane Christine Hahn
May 26, 2012·Microbial Pathogenesis·Melyssa NegriRosário Oliveira
Apr 26, 2013·Journal of Clinical Microbiology·Pilar EscribanoJesús Guinea
Jul 3, 2013·Revista iberoamericana de micología·Alessandra Ribeiro de FreitasTerezinha Inez Estivalet Svidzinski

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Citations

Oct 31, 2017·Frontiers in Microbiology·Diana L Zuza-AlvesGuilherme M Chaves
Dec 22, 2017·Revista Do Instituto De Medicina Tropical De São Paulo·Gláucia Moreira Espíndola LimaAnamaria Mello Miranda Paniago
Feb 22, 2021·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Heliara Maria Spina CanelaMárcia Eliana da Silva Ferreira

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