Genotyping of Porcine teschovirus from nervous tissue of pigs with and without polioencephalomyelitis in Indiana

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Dinesh S BangariGregory W Stevenson

Abstract

Porcine teschovirus (PTV) was isolated in cell culture and/or demonstrated by polymerase chain reaction in samples of brain and/or spinal cord in pigs in Indiana during the 2002-2007 period. Testing was initiated on pigs originating from populations exhibiting nervous clinical disease and/or pigs with microscopic lesions in central nervous tissues, indicating viral encephalitis and/or myelitis. Virus was demonstrated in pigs with and without lesions as well as with and without nervous clinical disease. Nucleotide sequence analysis of the 5'-nontranslated region of the viral genome revealed that these isolates had low-level genetic heterogeneity but were homologous to porcine PTV serotype 1 (PTV-1). These findings indicate that low-to-moderate virulence strains of PTV with some homology to PTV-1 are endemic in many swineherds of Indiana and are associated with subclinical and clinical nervous disease in weaned pigs.

References

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Citations

Dec 24, 2013·Tropical Animal Health and Production·Daiane Güllich DoninAmauri Alcindo Alfieri
Oct 11, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Cristina Cano-GómezMiguel Ángel Jiménez-Clavero
May 19, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Ming Y DengSamia Metwally
Jan 15, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Raquel A LemeAmauri A Alfieri
Oct 17, 2017·Transboundary and Emerging Diseases·T YangX Ren
Feb 13, 2020·BMC Veterinary Research·Sandra VremanJeroen Kortekaas
Dec 11, 2019·Tropical Animal Health and Production·Pradeep K RayG Saikumar
May 22, 2020·International Journal of Peptide Research and Therapeutics·Antara BarmanSupriyo Chakraborty
Jul 25, 2020·Translational Animal Science·Jordan T GebhardtSteve C Henry
May 24, 2021·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Márcia Elisa HammerschmittDavid Driemeier

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Methods Mentioned

BETA
PCR
reverse transcription PCR

Software Mentioned

Lasergene
MegAlign ClustalW

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