PMID: 9438655Jan 23, 1998Paper

Gentamicin-induced Bartter-like syndrome

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
D Landau, K K Kher

Abstract

Gentamicin is well known to be associated with nephrotoxicity, including acute renal failure and renal tubular dysfunction. A Bartter-like syndrome has also been described as a toxic manifestation of gentamicin therapy in adults, but this nephrotoxic syndrome has not been well characterized in children. In this report we describe the clinical course of four patients with gentamicin-associated Bartter-like syndrome. These patients ranged in age from 4 months to 17 years; they all demonstrated evidence of renal tubulopathy, primarily affecting the distal nephron. Hypocalcemia, hypomagnesemia, alkalosis, and hypokalemia were the main manifestations in these patients. After discontinuation of gentamicin, recovery of the renal tubular functions and resolution of the electrolyte abnormalities were complete in all patients.

Citations

Feb 5, 2011·Current Opinion in Pediatrics·Katherine TwombleyJyothsna Gattineni
Apr 15, 2009·Antimicrobial Agents and Chemotherapy·João F P OliveiraEmmanuel A Burdmann
Mar 9, 2007·Neonatology·Vasileios I GiaprosStyliani K Andronikou
Mar 2, 2012·American Journal of Nephrology·Chien-Te LeeYeong-Hau H Lien
Nov 29, 2008·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·R VieuxJ-M Hascoët
Mar 16, 2005·The American Journal of the Medical Sciences·Chu-Lin ChouShih-Hua Lin
Jun 29, 2005·Emergency Medicine Clinics of North America·Ilene ClaudiusRichard Boles
Mar 27, 2009·Nature Reviews. Nephrology·R ZietseE J Hoorn
Aug 27, 2005·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Jacob Atsmon, Eran Dolev
May 26, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Richard J GlassockFernando C Fervenza
May 14, 2020·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Periklis KatopodisKonstantinos P Katopodis
May 1, 1999·Antimicrobial Agents and Chemotherapy·M P Mingeot-Leclercq, P M Tulkens
Feb 11, 2021·Clinical Kidney Journal·Oluwatoyin Fatai Bamgbola, Youssef Ahmed
Jul 20, 2021·Pharmacology Research & Perspectives·George LiamisHaralampos Milionis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

The American Journal of the Medical Sciences
Chu-Lin ChouShih-Hua Lin
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Chi-Chih HungHung-Chun Chen
Journal of Perinatology : Official Journal of the California Perinatal Association
Sudhish Chandra, Rita Verma
Toxicology in Vitro : an International Journal Published in Association with BIBRA
H McGlynn, M P Ryan
© 2021 Meta ULC. All rights reserved