Geographic mapping of choroidal thickness in myopic eyes using 1050-nm spectral domain optical coherence tomography

Journal of Innovative Optical Health Sciences
Qinqin ZhangRuikang K Wang

Abstract

To provide a geographical map of choroidal thickness (CT) around the macular region among subjects with low, moderate and high myopia. 20 myopic subjects (n = 40 eyes) without other identified pathologies participated in this study: 20 eyes of ≤ 3 diopters (D) (low myopic), 10 eyes between -3 and -6D (moderate myopic), and 10 eyes of ≥ 6D (high myopic). The mean age of subjects was 30.2 years (± 7.6 years; range, 24 to 46 years). A 1050 nm spectral-domain optical coherence tomography (SD-OCT) system, operating at 120 kHz imaging rate, was used in this study to simultaneously capture 3D anatomical images of the choroid and measure intraocular length (IOL) in the subject. The 3D OCT images of the choroid were segmented into superior, inferior, nasal and temporal quadrants, from which the CT was measured, representing radial distance between the outer retinal pigment epithelium (RPE) layer and inner scleral border. Measurements were made within concentric regions centered at fovea centralis, extended to 5 mm away from fovea at 1 mm intervals in the nasal and temporal directions. The measured IOL was the distance from the anterior cornea surface to the RPE in alignment along the optical axis of the eye. Statistical analysis was per...Continue Reading

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Citations

Oct 21, 2015·Progress in Retinal and Eye Research·Daniela FerraraJay S Duker
Jul 19, 2019·Investigative Ophthalmology & Visual Science·Sen ZhangXiangtian Zhou
Sep 13, 2019·Journal of Ophthalmology·Francisco de Asís Bartol-PuyalLuis Pablo
Apr 1, 2017·European Journal of Ophthalmology·Amany A El-ShazlyWalid M A El-Zawahry

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Methods Mentioned

BETA
light scattering

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