Geographical distribution of a seropositive myasthenia gravis population

Muscle & Nerve
Anne Taraldsen HeldalFredrik Romi

Abstract

To assess age- and sex-specific myasthenia gravis (MG) occurrence and incidence in the different geographical regions in Norway and thereby to identify factors that may contribute to the development of MG. Multiple Poisson regression analysis was used to assess variation in incidence dependent on year, gender and onset age in five geographically defined health regions. The study population comprised 419 individuals with first time seropositive tests from 1995 to 2007. Annual MG incidence ranged from < 1 to 14 per million, with an average of 7.04 per million for all five health regions combined. This is the first nation-wide epidemiological study of seropositive MG that elucidates the geographical differences within a country. The incidence of seropositive MG did not vary significantly between the regions. Mid-Norway tended to have a higher incidence, and North tended to have a lower incidence.

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Citations

Aug 14, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·E G PedersenD Gaist
Mar 29, 2013·Autoimmunity Reviews·Alexander MarxPhilipp Ströbel
Aug 16, 2013·Current Opinion in Neurology·Luis Querol, Isabel Illa
Jul 26, 2014·Muscle & Nerve·Busisiwe MombaurJeannine M Heckmann
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Sep 10, 2020·Neurología : publicación oficial de la Sociedad Española de Neurología·D A García EstévezD Rodríguez Gómez

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