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Geometric constraints dominate the antigenic evolution of influenza H3N2 hemagglutinin

bioRxiv

Jan 22, 2015

Austin G. Meyer, Claus O. Wilke

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Abstract

We have carried out a comprehensive analysis of the determinants of human influenza A H3 hemagglutinin evolution, considering three distinct predictors of evolutionary variation at individual sites: solvent accessibility (as a proxy for protein fold stability and/or conservation), exper...read more

Mentioned in this Paper

Protein Folding
Proximal
Three-dimensional
Influenza virus vaccine
Genome
Supernumerary Maxillary Right Lateral Primary Incisor
NRBP protein, human
Site
Virus
Hemagglutinin
9
Paper Details
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  • Geometric constraints dominate the antigenic evolution of influenza H3N2 hemagglutinin

    bioRxiv

    Jan 22, 2015

    Austin G. Meyer, Claus O. Wilke

    PMID: 990014183

    DOI: 10.1101/014183

    Abstract

    We have carried out a comprehensive analysis of the determinants of human influenza A H3 hemagglutinin evolution, considering three distinct predictors of evolutionary variation at individual sites: solvent accessibility (as a proxy for protein fold stability and/or conservation), exper...read more

    Mentioned in this Paper

    Protein Folding
    Proximal
    Three-dimensional
    Influenza virus vaccine
    Genome
    9
    Paper Details
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