Geometrical tracking accuracy and appropriate PTV margins for robotic radiosurgery of liver lesions by SBRT

Acta Oncologica
Ming LiuEric Vandervoort

Abstract

Purpose: To assess the geometrical accuracy and estimate adequate PTV margins for liver treatments using the Synchrony respiratory tracking system. Material and methods: Treatment log files are analyzed for 72 liver patients to assess tracking accuracy. The tracking error is calculated as the quadratic sum of the correlation, the predictor and the beam positioning errors. Treatment target rotations and rigid body errors reported by the system are also evaluated. The impact of uncorrected rotations is assessed by rotating the planned dose distribution and reassessing target coverage. Total PTV margins are estimated by summing in quadrature tracking errors and rigid body errors. Relationships are explored between tracking errors, model linearity and motion amplitudes of internal and external markers. Results: Margins of 3, 2, 2 mm in SUP-INF, LT-RT and ANT-POST directions, respectively, are sufficient to account for tracking and beam positioning errors for 95% of patients. If rigid body error is also considered, margins increase to 4 mm isotropic. Rotations could not be corrected for 92% of patients due to imperfect fiducial implantation and limitations in the magnitude of corrections that the system can apply. Uncorrected rotati...Continue Reading

References

Apr 24, 2001·International Journal of Radiation Oncology, Biology, Physics·K M Langen, D T Jones
Apr 4, 2002·Medical Physics·Martin J Murphy
Apr 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Cihat Ozhasoglu, Martin J Murphy
Jul 4, 2002·International Journal of Radiation Oncology, Biology, Physics·Yvette SeppenwooldeKazuo Miyasaka
Oct 8, 2003·Medical Physics·Daniel A Low, James F Dempsey
Jan 31, 2004·Seminars in Radiation Oncology·Hiroki ShiratoShinichi Shimizu
Apr 9, 2005·International Journal of Radiation Oncology, Biology, Physics·David P GiergaGeorge T Y Chen
Nov 22, 2005·International Journal of Radiation Oncology, Biology, Physics·Mark Peter LangerVan Thai
Jun 23, 2006·Physics in Medicine and Biology·S Webb
Jun 9, 2007·Medical Physics·Markus WendlingMarcel van Herk
Apr 15, 2008·International Journal of Radiation Oncology, Biology, Physics·Xing-Qi LuStuart M Berman
May 6, 2008·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Cihat OzhasogluDwight E Heron
Aug 13, 2008·Physics in Medicine and Biology·Christos Antypas, Evaggelos Pantelis
Apr 14, 2009·International Journal of Radiation Oncology, Biology, Physics·Mischa HoogemanBen Heijmen
Sep 8, 2010·Technology in Cancer Research & Treatment·W KilbyC R Maurer
Apr 19, 2011·International Journal of Radiation Oncology, Biology, Physics·Kathleen MalinowskiWarren D D'Souza
Aug 6, 2011·Medical Physics·Sonja DieterichCheng Yu
Oct 4, 2011·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Amanda J CherpakGad Perry
Jan 3, 2012·International Journal of Radiation Oncology, Biology, Physics·Michael VelecKristy K Brock
Mar 21, 2012·International Journal of Radiation Oncology, Biology, Physics·Kathleen T MalinowskiWarren D D'Souza
Jun 16, 2012·BMC Medical Research Methodology·Morten W Fagerland
Jun 4, 2014·Practical Radiation Oncology·Salma K JabbourLaura A Dawson
Sep 10, 2014·International Journal of Radiation Oncology, Biology, Physics·Qianyi XuTamara LaCouture
Dec 11, 2014·Journal of Applied Clinical Medical Physics·Alejandro FlorianoAlberto Sánchez-Reyes
Feb 17, 2015·Clinical Oncology : a Journal of the Royal College of Radiologists·K L Aitken, M A Hawkins
Nov 5, 2015·International Journal of Radiation Oncology, Biology, Physics·Jeff D WinterTom Chow
May 30, 2016·Radiation Oncology·Nicolaus AndratschkeOliver Blanck
Jan 11, 2017·Technology in Cancer Research & Treatment·Anna K PaulssonMartina Descovich
Mar 1, 2017·International Journal of Radiation Oncology, Biology, Physics·Mark ChanOliver Blanck
Sep 7, 2017·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Susanne SteraOliver Blanck
Jan 30, 2018·Journal of Applied Clinical Medical Physics·Eric VandervoortDominic Béliveau Nadeau
Feb 7, 2018·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Judit Boda-HeggemannOliver Blanck
Aug 3, 2018·Technology in Cancer Research & Treatment·Stephanie K SchaubSmith Apisarnthanarax

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