Mar 30, 2014

Geometry shapes evolution of early multicellularity

BioRxiv : the Preprint Server for Biology
Eric LibbyBen Kerr

Abstract

Organisms have increased in complexity through a series of major evolutionary transitions, in which formerly autonomous entities become parts of a novel higher-level entity. One intriguing feature of the higher-level entity after some major transitions is a division of reproductive labor among its lower-level units. Although it can have clear benefits once established, it is unknown how such reproductive division of labor originates. We consider a recent evolution experiment on the yeast Saccharomyces cerevisiae as a unique platform to address the issue of reproductive differentiation during an evolutionary transition in individuality. In the experiment, independent yeast lineages evolved a multicellular “snowflake-like” cluster form in response to gravity selection. Shortly after the evolution of clusters, the yeast evolved higher rates of cell death. While cell death enables clusters to split apart and form new groups, it also reduces their performance in the face of gravity selection. To understand the selective value of increased cell death, we create a mathematical model of the cellular arrangement within snowflake yeast clusters. The model reveals that the mechanism of cell death and the geometry of the snowflake interact...Continue Reading

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Mentioned in this Paper

Mechanism of Cell Death
Saccharomyces cerevisiae allergenic extract
Reproduction
Labor (Childbirth)
Face
Yeasts
Cell Count
Snowflake Retinal Degeneration
Anatomical Space Structure
Cell Differentiation Process

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