George III: a revised view of the royal malady

Journal of the History of the Neurosciences
S Brownstein

Abstract

George III of England's episodic psychotic illness is described. The data has previously been used to substantiate the diagnosis of an unlikely hereditary metabolic disease, porphyria. A scientific perspective, aimed at removing psychiatric diagnosis from dependence on subjective evaluations, is corrected by the diagnosis of a mood disorder. His unipolar mania of late onset is a syndrome, the sine qua non of bipolar disorder, in this instance complicated by the toxicity of quinine, antimony, and purgatives.

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Citations

Sep 10, 2011·Clinical Medicine : Journal of the Royal College of Physicians of London·Timothy Peters
Mar 1, 2010·History of Psychiatry·Timothy J Peters, D Wilkinson
Mar 1, 2010·History of Psychiatry·Timothy J Peters, Allan Beveridge

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