PMID: 6164475Apr 1, 1981Paper

Germ-cell tumors in patients with apparently normal testes

Cancer
M E Burt, N Javadpour

Abstract

Germ-cell tumors occasionally occur in patients with clinically normal testes. Although data exist correlating serial serum hCG and AFP in gem-cell neoplasms of testicular origin, the literature is sparse concerning the patients presenting with clinically normal testes. Presented in this report are data to confirm the reliability and usefulness of serial serum hCG and AFP levels in those patients with extragonadal germ-cell tumors and apparently normal testes. Six patients with nonseminomatous extragonadal tumors are presented. Serial serum hCG and AFP levels correlated with the clinical course in each of the patients. The serum hCG and/or AFP decreased with response to therapy and increased with progression of disease. It is concluded that serial serum hCG and AFP determinations are very useful parameters to evaluate and follow the course of disease in this group of patients.

References

Dec 1, 1978·The Journal of Urology·N Javadpour
Dec 1, 1978·Cancer·J P DonohueJ M Perez
Feb 1, 1971·The Journal of Urology·D C Utz, M F Buscemi
Jul 15, 1972·American Journal of Obstetrics and Gynecology·J L VaitukaitisG T Ross
Jun 1, 1953·Thorax·M J LYNCH, G L BLEWITT
Apr 21, 1955·The New England Journal of Medicine·L B WOOLNERJ W KIRKLIN

❮ Previous
Next ❯

Citations

Jan 1, 1988·International Urology and Nephrology·M Hornák, D Ondrus
Jan 1, 1994·International Urology and Nephrology·J I Lopez, J C Angulo
May 1, 1983·Cancer Genetics and Cytogenetics·R N SchimkeR L Stephens
Sep 23, 1997·The American Journal of Surgical Pathology·C A Moran, S Suster
Oct 23, 1997·The American Journal of Surgical Pathology·C A Moran, S Suster
Oct 23, 1997·The American Journal of Surgical Pathology·C A Moran, S Suster
Jul 5, 2006·The American Journal of Surgical Pathology·Bonnie L Balzer, Thomas M Ulbright
Dec 1, 1983·Thorax·D ParkerK D Bagshawe
Feb 1, 1983·Chest·G H Clamon
Jan 16, 2003·Chest·Giulio RossiLucia Longo
Sep 19, 2009·The Journal of Urology·Javier C AnguloJosé I López
Nov 1, 1983·The American Journal of Medicine·J D Hainsworth, F A Greco
Dec 26, 2003·Seminars in Diagnostic Pathology·J Carlos Manivel, Stefan Pambuccian
Apr 1, 1982·The Annals of Thoracic Surgery·N J VogelzangB J Kennedy
Jul 1, 1988·The Journal of Urology·F H DexeusS Ogden
May 1, 1986·The Journal of Urology·A BöhleJ R Scheidegger
Aug 1, 1983·The Journal of Urology·J M BockrathH L Neiman
Apr 1, 1992·The Journal of Urology·T W CrainG D Sandberg

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.