Germ-layer surface tensions and "tissue affinities" in Rana pipiens gastrulae: quantitative measurements

Developmental Biology
G S DavisMalcolm S Steinberg

Abstract

The morphogenetic properties causing germ-layer spreading and stratification in amphibian gastrulation were called "tissue affinities" by Holtfreter. The differential adhesion hypothesis (DAH) attributes such liquid-like tissue rearrangements to forces generated by intercellular adhesions within and between the migrating cell populations. This theory predicts that, among the primary germ layers, the cohesiveness of deep ectoderm should be the greatest, that of deep mesoderm should be intermediate, and that of deep endoderm should be the least. Also, the cohesiveness of differentiating neural ectoderm should increase after induction, causing it to internalize and segregate from epidermis. The DAH also explains why the cohesiveness of "liquid" tissues, whose cells are free to rearrange, should be measurable as tissue surface tensions. Using a specially designed tissue surface tensiometer, we demonstrate that (i) aggregates of Rana pipiens deep germ layers do possess liquid-like surface tensions, (ii) their surface tension values lie in precisely the sequence necessary to account for germ-layer stratification in vitro and in vivo, and (iii) the surface tension of deep ectoderm just underlain by the archenteron roof is twice that o...Continue Reading

References

May 8, 1991·The Journal of Comparative Neurology·J L Smith, G C Schoenwolf
Jan 1, 1989·Critical Reviews in Biochemistry and Molecular Biology·P B Armstrong
Oct 22, 1988·The Journal of Comparative Neurology·G C Schoenwolf
Sep 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·H M Phillips, M S Steinberg
Jan 4, 1994·Proceedings of the National Academy of Sciences of the United States of America·M S Steinberg, M Takeichi
Dec 15, 1996·Developmental Biology·M S Steinberg
Mar 1, 1993·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·J A Glazier, F Graner
Apr 4, 1994·Physical Review Letters·R A FotyM S Steinberg
Sep 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·M S STEINBERG
Feb 1, 1964·Developmental Biology·J P TRINKAUS, J P LENTZ
Oct 1, 1962·Proceedings of the National Academy of Sciences of the United States of America·M S Steinberg

❮ Previous
Next ❯

Citations

Nov 20, 1997·Journal of Cellular Physiology·M S Steinberg, R A Foty
Sep 29, 2007·Biomechanics and Modeling in Mechanobiology·Xiaohai WanSharon R Lubkin
Feb 26, 2013·In Vitro Cellular & Developmental Biology. Animal·Ayano HarataSetsunosuke Ihara
Mar 21, 2003·Developmental Biology·Duke DuguayMalcolm S Steinberg
Oct 6, 1999·Current Opinion in Cell Biology·M S Steinberg, P M McNutt
Oct 8, 2004·Nature·Takashi Hayashi, Richard W Carthew
Mar 28, 2008·Nature Cell Biology·M KriegC-P Heisenberg
Jun 19, 2004·Computer Methods in Biomechanics and Biomedical Engineering·G Wayne Brodland, Colin J Wiebe
Jul 14, 2011·Physical Biology·Michelangelo von Dassow, Lance A Davidson
May 19, 2011·Journal of Visualized Experiments : JoVE·Ramsey Foty
Aug 2, 2013·Future Oncology·Ramsey A Foty
Feb 26, 2004·Proceedings of the National Academy of Sciences of the United States of America·Karoly JakabGabor Forgacs
Mar 29, 2001·Proceedings of the National Academy of Sciences of the United States of America·P L RyanM S Steinberg
Feb 6, 2010·Expert Opinion on Biological Therapy·Richard P ViscontiVladimir Mironov
Oct 28, 2015·The Journal of Cell Biology·Evan Heller, Elaine Fuchs
Jan 26, 2012·Cell Adhesion & Migration·Alicia A BlancasKara E McCloskey
Jul 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·M Lisa ManningEva-Maria Schoetz
Jan 19, 2016·Seminars in Cell & Developmental Biology·Adam Navis, Celeste M Nelson
Mar 30, 2016·Drug Discovery Today·Amish Asthana, William S Kisaalita
Jun 1, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Michael J Hill, Debanjan Sarkar
Mar 16, 2017·Development·Mijo Simunovic, Ali H Brivanlou
Aug 24, 2006·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·José M Pérez-Pomares, Ramsey A Foty
Jun 23, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Dongxuan JiaRamsey A Foty
Jan 30, 2008·Birth Defects Research. Part C, Embryo Today : Reviews·Michelangelo von Dassow, Lance A Davidson
Dec 20, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Michelangelo von Dassow, Lance A Davidson
Aug 30, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Karoly JakabGabor Forgacs
Sep 14, 2000·Proceedings of the National Academy of Sciences of the United States of America·E Palsson, H G Othmer
Jun 25, 2020·Scientific Reports·Rakesh Kumar BanoteHenrik Zetterberg
Sep 10, 2013·Wiley Interdisciplinary Reviews. Developmental Biology·Ramsey A Foty, Malcolm S Steinberg
May 5, 2020·Frontiers in Bioengineering and Biotechnology·Abdel Rahman Abdel Fattah, Adrian Ranga
Nov 29, 2017·Developmental Biology·Kevin Chiou, Eva-Maria S Collins
Jul 1, 2020·Seminars in Cell & Developmental Biology·François Fagotto
Oct 17, 2015·Journal of Cell Science·Rudolf Winklbauer
Dec 17, 2002·Journal of Cell Science·Elizabeth E RobinsonRamsey A Foty
Sep 25, 2014·Development·Robert DavidRudolf Winklbauer
Aug 6, 2000·Developmental Biology·S WackerR Winklbauer
Jan 15, 2005·Developmental Biology·Ramsey A Foty, Malcolm S Steinberg
Sep 5, 2021·Development, Growth & Differentiation·Sohei SuzukiHiroyuki Kaneko

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.