German Database of Gene Transfer Clinical Trials. Implementation of a central registry of gene transfer clinical trials in Germany

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
G Dreier, K Cichutek

Abstract

Continuous biotechnical development and rapid increase in knowledge in the field of research on human gene transfer raise scientific, medical, and ethical considerations in the scientific community and general public. Dissemination of new scientific findings is needed. Gene transfer studies today not only focus on monogenic diseases or life-threatening conditions such as cancer, but also comprise trials for diagnosis and prophylaxis and common medical conditions such as cardiovascular disease. This raises special attention and public discussion and requires even more the systematic monitoring and assessment of clinical trails being conducted. Whereas the number of gene transfer trials in the USA can be clearly specified, this had not been possible in Germany prior to the establishment of the DeReG database. The aim is implementation of a permanent registry comprehending all clinical gene transfer trials being conducted in Germany. Only a complete and updated database serves as a common foundation of knowledge for various groups and facilitates addressing scientific projects.

Citations

Mar 25, 2009·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·G DreierM Schumacher
Mar 29, 2002·British Journal of Haematology·G D Schmidt-Wolf, I G H Schmidt-Wolf
Feb 1, 2009·Journal of Evidence-based Medicine·Hanna HasselblattMartin Schumacher

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